Table 1. Absolute Mean LC Discharge Rates for Each Experimental Condition.
|
Spontaneous (Hz) |
Evoked (counts) |
|||||
|---|---|---|---|---|---|---|
| Baseline | Stressor/Control Manipulation | Baseline | Stressor/Control Manipulation | |||
| Day 1 | ||||||
| Adult-Con | (n=4, 17 cells) | 1.07±0.13 | 1.13±0.16 | (n=4, 17 cells) | 23±4 | 19±4 |
| Adult-Stress | (n=4, 15 cells) | 2.47±0.56 | 3.29±0.72* | (n=3, 11 cells) | 32±8 | 18±8 |
| Adolescent-Con | (n=3, 11 cells) | 1.72±0.27 | 1.50±0.21 | (n=3, 11 cells) | 25±3 | 24±4 |
| Adolescent-Stress | (n=4, 15 cells) | 1.16±0.12 | 1.75±0.25*** | (n=3, 13 cells) | 42±13 | 15±4* |
| Day 5 | ||||||
| Adult-Con | (n=3, 10 cells) | 1.51±0.29 | 1.39±0.22 | (n=3, 10 cells) | 28±5 | 16±4 |
| Adult-Stress | (n=4, 13 cells) | 1.42±0.30# | 2.50±0.20** | (n=3, 10 cells) | 21±10 | 16±8 |
| Adolescent-Con | (n=3, 7 cells) | 1.26±0.10 | 1.30±0.22 | (n=3, 7 cells) | 30±5 | 30±4 |
| Adolescent-Stress | (n=4, 14 cells) | 1.98±0.24# | 1.74±0.28 | (n=4, 14 cells) | 37±5 | 24±4** |
Absolute mean LC spontaneous discharge and sensory evoked activity at baseline and during exposure to the social stressor (or control manipulation) in adolescent and adult animals on days 1 and 5. Animal and cell numbers for each value are provided. *p<0.05, **p<0.01, ***p<0.001; two-way rmANOVA comparison w/ controls. #p<0.05; post hoc comparison w/ day 1 values.