Table 1.
Demographic, health, cognitive, and processing speed data on the Lothian Birth Cohorts of 1921 and 1936.
| Lothian Birth Cohort 1921 | Lothian Birth Cohort 1936 | Mean comparison (p-value) |
Cohen's d | Variance comparison (p-value) |
|
|---|---|---|---|---|---|
| Sex: n male, n female | 112, 132 | 481, 469 | .20 | – | – |
| Hypertension: n (%) | 121 (49.6) | 370 (38.9) | .003 | – | – |
| Diabetes: n (%) | 16 (6.6) | 74 (7.8) | .59 | – | – |
| Cardiovascular disease: n (%) | 39 (16.2) | 222 (23.4) | .018 | – | – |
| Cerebrovascular disease: n (%) | 17 (7.0) | 44 (4.6) | .14 | – | – |
| Grip strength (kg) | 25.2 (9.1) | 29.8 (10.1) | < .001 | 0.48 | .004 |
| Mini-Mental State Examination score | 28.3 (1.5) | 28.9 (1.2) | < .001 | 0.44 | < .001 |
| Moray House Test, age 11 (out of 76) | 47.7 (11.4) | 49.3 (11.7) | .065 | 0.14 | .78 |
| Age when sat Moray House Test, age 11 | 10.9 (0.29) | 10.9 (0.28) | .177 | 0.00 | .377 |
| Moray House Test in older age (out of 76) | 61.5 (9.3) | 64.9 (8.0) | < .001 | 0.39 | < .001 |
| Age when sat Moray House Test in older age | 79.1 (0.60) | 69.5 (0.84) | – | – | – |
| Age at all other assessments in older age | 83.3 (0.53) | 69.5 (0.84) | – | – | – |
| National Adult Reading Test (out of 50) | 35.4 (7.6) | 34.7 (8.0) | .21 | 0.09 | .22 |
| Wechsler Digit Symbol Substitution score | 42.8 (11.9) | 57.5 (12.4) | < .001 | 1.21 | .51 |
| Simple reaction time mean (ms) | 306.2 (65.9) | 273.8 (53.1) | < .001 | 0.54 | < .001 |
| 4-Choice reaction time mean (ms) | 780.2 (128.4) | 636.0 (80.5) | < .001 | 1.35 | < .001 |
| Inspection time total score (out of 150) | 104.8 (10.4) | 112.9 (10.0) | < .001 | 0.79 | .15 |
| General speed | − 1.01 (1.03) | 0.26 (0.81) | < .001 | 1.28 | < .001 |