Table 5.
Drug | Price per pack (€)a [53] | Unit per pack | Unit price (€) | Cost per 3 months (€)b | Comments/sources [31–36, 38] |
---|---|---|---|---|---|
PLAI 150 mg | 456.50 | 1 | 456.50 [76] | Inpatientc: 501 Outpatient: 1265 Prevention phase: 752 |
Initiation phase: PLAI 150 mg at D1, 100 mg at D8, 75 mg/month Prevention phase: 75 mg/month |
PLAI 100 mg | 306.87 | 1 | 306.87 [77] | ||
PLAI 75 mg | 250.73 | 1 | 250.73 [78] | ||
RLAI 37.5 mg/2 ml | 130.86 | 1 | 130.86 [79] | Inpatientc: 530 Outpatient: 806 Prevention phase: 785 |
Initiation and prevention phase: 37.5 mg biweekly (equivalent to 75 mg of PLAI monthly) Note: 2-week oral supplementation during the initiation phase |
Oral risperidone 4 mg | 29.77 | 30 | 0.99 [80] | ||
ALAI 400 mg | 268.51 | 1 | 268.51 [81] | Inpatientc: 537 Outpatient: 853 Prevention phase: 806 |
|
Oral aripiprazole | 95.92 | 28 | 3.43 [82] | Oral aripiprazole: 15 mg/day | |
OLAI | 218.42 | 1 | NA | Inpatientc: 874 Outpatient: 1311 Prevention phase: 1311 |
Only at the hospital. Hypothesis: half-day hospitalisation cost |
OO | 43.78 | 28 | 1.56 [83] | Inpatientc: 874 Outpatient: 14 Prevention phase: 141 |
OO: 10 mg per day |
HLAI | 16.53 | 5 | 3.31 [84] | Inpatientc: 17 Outpatient: 50 Prevention phase: 50 |
5 ml/injection biweekly |
Clozapine | 16.08 | 28 | 0.57 [85] | Outpatient: 155 Prevention phase: 155 |
Maximum 300 mg per day |
ALAI aripiprazole long-acting injectable, HLAI haloperidol long-acting injectable, OLAI olanzapine long-acting injectable, OO oral olanzapine, PLAI paliperidone long-acting injectable, RLAI risperidone long-acting injectable
aPublic price all taxes
bCost per 3 months reflecting when the initiation phase started
cThe inpatient initiation phase includes a period at the hospital and an outpatient setting period after discharge. The reported price is the price of the outpatient setting period only (i.e. 3 months minus the hospitalisation period), since it is assumed that medication costs at hospital were included in the daily price of hospitalisation (i.e. €436.8)