Table 5:
Statistical results for Morris water maze reversal performance in Fmr1 and WT mice
| Effect | Data structure | Type of test | Power | df (between) | df (within) | F | p |
|---|---|---|---|---|---|---|---|
| Latency reversal-genotype | Sphericity violated | Mixed-model ANOVA | 0.05 | 1 | 22 | 0.001 | 0.97 |
| Latency reversal-day | Sphericity violated | Mixed-model ANOVA with Greenhouse–Geisser correction | 1.00 | 2.16 | 47.58 | 10.12 | 0.0002 |
| Latency reversal-interaction | Sphericity violated | Mixed-model ANOVA with Greenhouse–Geisser correction | 0.22 | 2.16 | 47.58 | 0.82 | 0.5 |
| Distance reversal-genotype | Sphericity violated | Mixed-model ANOVA | 0.07 | 1 | 22 | 0.16 | 0.7 |
| Distance reversal-day | Sphericity violated | Mixed-model ANOVA with Greenhouse–Geisser correction | 0.99 | 2.17 | 47.66 | 7.91 | 0.0008 |
| Distance reversal-interaction | Sphericity violated | Mixed-model ANOVA with Greenhouse–Geisser correction | 0.37 | 2.17 | 47.66 | 1.46 | 0.2 |
| Speed reversal-genotype | Sphericity passed | Mixed-model ANOVA | 0.05 | 1 | 22 | 0.04 | 0.8 |
| Speed reversal-day | Sphericity passed | Mixed-model ANOVA | 0.41 | 3 | 66 | 1.63 | 0.2 |
| Speed reversal-interaction | Sphericity passed | Mixed-model ANOVA | 0.33 | 3 | 66 | 1.28 | 0.3 |
| WT reversal quadrant time | Sphericity violated | Repeated-measures ANOVA with Greenhouse–Geisser correction and post hoc Dunnett’s test | 0.80 | 1.94 | 21.37 | 4.08 | 0.3 |
| FMR1 reversal quadrant time | Sphericity violated | Repeated-measures ANOVA with Greenhouse–Geisser correction and post hoc Dunnett’s test | 1.00 | 2.02 | 22.24 | 20.84 | 0.000008 |
| WT reversal platform crossings | Sphericity passed | Repeated-measures ANOVA with post hoc Dunnett’s test | 0.91 | 3 | 33 | 5.41 | 0.004 |
| FMR1 reversal platform crossings | Sphericity violated | Repeated-measures ANOVA with Greenhouse–Geisser correction and post hoc Dunnett’s test | 1.00 | 1.97 | 21.68 | 9.91 | 0.0009 |