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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1960 May;13(3):246–248. doi: 10.1136/jcp.13.3.246

THE DETERMINATION OF SERUM IRON AFTER THE INTRAVENOUS INJECTION OF IRON-DEXTRAN

D Webster 1
PMCID: PMC480060  PMID: 13843331

Abstract

A rapid technique for the determination of iron in serum, after the intravenous injection of iron-dextran, is presented.

Dithionite is used for the reduction of ferric to ferrous iron.

The use of a detergent solution enables protein precipitation to be omitted.

The iron reagent, 4: 7-diphenyl-1: 10-phenanthroline, and its ferrous complex are both soluble in the dilute detergent solution.

Lipaemic serum can be used without affecting the results.

The recovery of added ferric iron, as iron-dextran, is quantitative.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. MACKENZIE A., TINDLE J. Determination of plasma-volume using intravenous iron dextran. Lancet. 1959 Feb 14;1(7068):333–335. doi: 10.1016/s0140-6736(59)90313-7. [DOI] [PubMed] [Google Scholar]
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