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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Nature. 2015 May 4;522(7556):368–372. doi: 10.1038/nature14352

Extended Data Figure 1. Synthesis algorithm for the selective labeling of RNA using PLOR method.

Extended Data Figure 1

All samples except for fully labeled 71nt-CN, S1+Lk1-CN, S1+Lk1-H, and 15N-104nt-TCV were synthesized following this algorithm. The initiation, elongation and termination stages are shown in green, blue and red, respectively. Various NTP combinations added during the elongation cycles depend on the desired labeling scheme.