. 2015 Aug 12;5(2):e1071007. doi: 10.1080/2162402X.2015.1071007

Table 3.

Relationship between the frequency either at baseline or at W12 of circulating T cell subsets and OS of MM patients.

T cell subset	OS	Mean^a Baseline	Standard Error	P
CD3⁺CD4⁺CD137⁺	< 24 mo.	0.17	0.20	0.04
	> 24 mo.	0.36	0.29
CD3⁺CD4⁺CD45RO⁺BTLA⁺	< 24 mo.	2.27	0.58	0.05
	> 24 mo.	6.64	2.25
CD3⁺CD8⁺CD45RA⁺CTLA-4⁺	< 24 mo.	2.06	0.55	0.02
	> 24 mo.	0.55	0.14
CD3⁺CD4⁺IL-17⁺	< 24 mo.	0.34	0.09	0.02
	> 24 mo.	1.74	0.60
CD3⁺CD8⁺IL-17⁺	< 24 mo.	0.38	0.10	0.02
	> 24 mo.	1.41	0.44
T cell subset	OS	Mean^a W12	Standard Error	P
CD3⁺ CD45RO⁺CD62L⁺	< 24 mo.	4.39	1.55	0.02
	> 24 mo.	12.36	3.18
CD3⁺ CD4⁺CD45RO⁺CD62L⁺	< 24 mo.	5.40	1.82	0.02
	> 24 mo.	14.34	3.24
CD3⁺CD4⁺CD45RA⁺BTLA⁺	< 24 mo.	4.63	1.28	0.01
	> 24 mo.	1.08	0.99
CD3⁺CD8⁺CD45RA⁺CTLA-4⁺	< 24 mo.	2.04	0.52	0.007
	> 24 mo.	0.41	0.11

The association between the frequency of circulating T cell subsets and long-term survival (OS>24 mo) of MM patients has been analyzed and the statistically significant results have been reported in the table. ^a: mean of the percentage of positive cells in PBMCs from melanoma patients; mo.: months.