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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1961 Mar;14(2):152–160. doi: 10.1136/jcp.14.2.152

The application of x-ray diffraction and electron microscopy to the study of human peripheral nerve obtained by biopsy

J B Finean 1,2, A L Woolf 1,2
PMCID: PMC480182  PMID: 13699577

Abstract

Human peripheral nerves obtained by biopsy from patients suffering from neuromuscular disorders have been studied by x-ray diffraction and electron microscopy. Few abnormal diffraction patterns have yet been recorded and their significance is not yet established. Electron micrographs have revealed wide variations in the numbers of myelinated fibres included in the nerve trunks and have facilitated a detailed study of the Schwann cell-axon relationships in the large numbers of unmyelinated fibres always present. Some indications of demyelination have been encountered.

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Selected References

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