Abstract
Blood lipids have been measured in sera from 750 cadavers. All nine fractions measured show a remarkably consistent pattern of differences between the various gross morbid anatomical forms of ischaemic heart disease. The highest mean values are found when an obvious coronary thrombus is present and those in simple atheromatous occlusion are nearly as high. When there is recognizable necrosis the values are considerably more normal.
The serum lipids show relatively little change due to autolysis, about one half of 1% per hour or less.
Lipoprotein levels assayed with Cl.welchii alpha toxin correlate well with disease states.
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- BURSTEIN M., SAMAILLE J. Sur une nouvelle méthode de dosage des beta-lipoprotéines sériques par l'héparine. C R Hebd Seances Acad Sci. 1956 Dec 17;243(25):2185–2187. [PubMed] [Google Scholar]
- DANGERFIELD W. G., SMITH E. B. An investigation of serum lipids and lipoproteins by paper electrophoresis. J Clin Pathol. 1955 May;8(2):132–139. doi: 10.1136/jcp.8.2.132. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ENTICKNAP J. B. Serum fatty acids after fatal heart-attacks. Lancet. 1960 Jan 2;1(7114):32–32. doi: 10.1016/s0140-6736(60)92724-0. [DOI] [PubMed] [Google Scholar]
- GLANVILLE J. N. Post-mortem serum cholesterol levels. Br Med J. 1960 Dec 24;2(5216):1852–1853. doi: 10.1136/bmj.2.5216.1852. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PERRIN J. The Nagler reaction in pathological sera and its use as a liver function test. J Clin Pathol. 1959 Sep;12:459–466. doi: 10.1136/jcp.12.5.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SCHLANG H. A., DAVIS D. R. Paper electrophoretic studies of postmortem serum proteins. Am J Med Sci. 1958 Oct;236(4):472–474. [PubMed] [Google Scholar]
- SCHLEYER F. Papierelektrophoretische Untersuchungen des Eiweissbildes von Leichenseren. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1954;221(4):306–311. [PubMed] [Google Scholar]
- SPAIN D. M., BRADESS V. A., GREENBLATT I. J. Possible factor in sudden and unexpected death during infancy. J Am Med Assoc. 1954 Sep 18;156(3):246–247. doi: 10.1001/jama.1954.02950030038011b. [DOI] [PubMed] [Google Scholar]
- STERN I., SHAPIRO B. A rapid and simple method for the determination of esterified fatty acids and for total fatty acids in blood. J Clin Pathol. 1953 May;6(2):158–160. doi: 10.1136/jcp.6.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]