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. 2015 Sep 11;4(2):e1086520. doi: 10.1080/21623996.2015.1086520

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 2. — Comparison of LIF intra-cellular signaling activity in mESCs derived from permissive and non-permissive genetic backgrounds. Permissiveness for derivation and maintenance of mESCs is determined by the balance between Stat3 and MAPK pathways downstream of LIF.