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. 1961 Nov;14(6):615–621. doi: 10.1136/jcp.14.6.615

Hereditary elliptocytic anaemia

R J L Davidson 1,2, W T Strauss 1,2
PMCID: PMC480304  PMID: 13883803

Abstract

A sibship with four cases of hereditary elliptocytic anaemia is described. The condition in this family may have arisen as a mutation in the mother of the sibship; affected members were unable to taste phenylthiocarbamide while normal members were tasters.

Experiments with 32P-orthophosphate in vitro did not show any evidence of biochemical upset as found in hereditary spherocytosis; thus a combination of congenital spherocytosis and elliptocytosis cannot be supported as the cause of the haemolytic state. Clinical evidence of haemolytic disease was accompanied by a tendency to excessive lysis in vitro.

Infection may play a part in the precipitation of anaemic crises in this as in other hereditary haemolytic anaemias.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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