Skip to main content
PMC home page
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1962 Mar;15(2):156–160. doi: 10.1136/jcp.15.2.156

Improved rapid methods for the determination of iron content and binding capacity of serum

R N Beale 1, J O Bostrom 1, R F Taylor 1
PMCID: PMC480366  PMID: 13866115

Abstract

Improved methods are described for the determination of serum iron (SeFe) and latent iron-binding capacity under controlled conditions of pH. As before, no precipitation or heating of the serum is required, and controls are not used. Unbuffered sulphonated bathophenanthroline is employed for colour development. Statistical data for 40 normals are presented and comparisons with other data are given; the effects of ageing of serum are studied.

Full text

PDF
156

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BEALE R. N., BOSTROM J. O., TAYLOR R. F. Rapid incremental methods for the determination of serum iron and iron-binding capacity. J Clin Pathol. 1961 Sep;14:488–495. doi: 10.1136/jcp.14.5.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DAVIES G., LEVIN B., OBERHOLZER V. G. The micro estimation of serum iron and iron-binding capacity in normals and in disease. J Clin Pathol. 1952 Nov;5(4):312–316. doi: 10.1136/jcp.5.4.312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. KOK D., WILD F. Serum iron determination. J Clin Pathol. 1960 May;13:241–245. doi: 10.1136/jcp.13.3.241. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. PIRRIE R. The influence of age upon serum iron in normal subjects. J Clin Pathol. 1952 Feb;5(1):10–15. doi: 10.1136/jcp.5.1.10. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. SCHADE A. L., OYAMA J., REINHART R. W., MILLER J. R. Bound iron and unsaturated iron-binding capacity of serum; rapid and reliable quantitative determination. Proc Soc Exp Biol Med. 1954 Nov;87(2):443–448. doi: 10.3181/00379727-87-21407. [DOI] [PubMed] [Google Scholar]
  6. Surgenor D. M., Koechlin B. A., Strong L. E. CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXXVII. THE METAL-COMBINING GLOBULIN OF HUMAN PLASMA. J Clin Invest. 1949 Jan;28(1):73–78. doi: 10.1172/JCI102056. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. TRINDER P. The improved determination of iron in serum. J Clin Pathol. 1956 May;9(2):170–172. doi: 10.1136/jcp.9.2.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. ZIZZA F., BLOCK M. The interrelationship of the serum iron, iron binding capacity and tissue iron. Acta Haematol. 1961 Jan;25:1–21. doi: 10.1159/000206500. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES