Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1962 Jul;15(4):314–323. doi: 10.1136/jcp.15.4.314

Acute disseminated encephalomyelitis, with massive necrosis of the spinal cord, probably due to antitetanus serum

A A Miller 1, F Ramsden 1
PMCID: PMC480405  PMID: 14473939

Abstract

The clinical and pathological findings are described of a fatal case of acute haemorrhagic leucoencephalitis and disseminated encephalomyelitis with acute necrosis of the white matter of the spinal cord. It is suggested that the reaction was a severe immunological response of an allergic nature, probably due to antitetanus serum.

Full text

PDF
314

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CAMPBELL B., GOOD R. A. Cytopathology of the brain and reticuloendothelial organs in allergic encephalitis in guinea pigs. Arch Neurol Psychiatry. 1950 Feb;63(2):298–310. doi: 10.1001/archneurpsyc.1950.02310200106009. [DOI] [PubMed] [Google Scholar]
  2. CSERMELY H. Demyelinating encephalomyelitis following use of antitetanus serum. AMA Arch Neurol Psychiatry. 1950 Nov;64(5):676–684. doi: 10.1001/archneurpsyc.1950.02310290072007. [DOI] [PubMed] [Google Scholar]
  3. HOFFMAN H. L. Acute necrotic myelopathy. Brain. 1955 Sep;78(3):377–394. doi: 10.1093/brain/78.3.377. [DOI] [PubMed] [Google Scholar]
  4. TOOGOOD J. H. Allergic reactions to antitetanus serum. Can Med Assoc J. 1960 Apr 30;82:907–912. [PMC free article] [PubMed] [Google Scholar]
  5. WILLIAMS H. W., CHAFEE F. H. Demyelinating encephalomyelitis in a case of tetanus treated with antitoxin. N Engl J Med. 1961 Mar 9;264:489–491. doi: 10.1056/NEJM196103092641005. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES