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. 1962 Sep;15(5):438–445. doi: 10.1136/jcp.15.5.438

Fatal recurrence of parathyroid carcinoma after seven years

J P Caley 1,2,1, E E Jones 1,2, D H Collins 1,2
PMCID: PMC480431  PMID: 14017871

Abstract

The case is reported of a woman who died at the age of 36 from parathyroid carcinoma. The removal, seven years earlier, of a large parathyroid tumour, judged at that time to be benign, was followed by a remission of symptoms for about four years after which they recurred. At necropsy, a well-differentiated parathyroid carcinoma showed local invasion and lymph-node metastases in the neck. Review of the original `adenoma' suggested that this growth might have been a carcinoma.

The total number of recorded cases of hyperfunctioning parathyroid carcinoma is still limited but has now reached at least 37. Carcinoma is rarely to be diagnosed except at necropsy; nevertheless, it seems to be the important cause of delayed recurrence of symptoms after parathyroidectomy. The evolution of the growth is often very slow.

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Selected References

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