Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1964 Mar;17(2):111–113. doi: 10.1136/jcp.17.2.111

Estimation of serum L. casei activity

I Chanarin 1, Valerie Berry 1
PMCID: PMC480696  PMID: 14149931

Abstract

Measurement of the serum Lactobacillus casei (`folic-acid') activity is widely used as an index of folic-acid deficiency. Present methods of assay result in recovery of about half the active material in normal serum. A modified method of assay is described which gives higher L. casei values and a clearer distinction between the sera of normal subjects and of patients with folic-acid deficiency.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAKER H., HERBERT V., FRANK O., PASHER I., HUTNER S. H., WASSERMAN L. R., SOBOTKA H. A microbiologic method for detecting folic acid deficiency in man. Clin Chem. 1959 Aug;5(4):275–280. [PubMed] [Google Scholar]
  2. HERBERT V. The assay and nature of folic acid activity in human serum. J Clin Invest. 1961 Jan;40:81–91. doi: 10.1172/JCI104240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. WATERS A. H., MOLLIN D. L. Studies on the folic acid activity of human serum. J Clin Pathol. 1961 Jul;14:335–344. doi: 10.1136/jcp.14.4.335. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES