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. 2015 Nov 9;7(1):729–744. doi: 10.18632/oncotarget.6327

Figure 2. HE4 promoted the proliferation, invasion and metastasis capacities of ovarian cancer cells in vitro.

Figure 2

The proliferation assay showed that HE4 promoted the proliferation of the ovarian cancer cells ES-2 and Caov-3 obviously (panel A, P < 0.05), compared with the mock group. Wound healing assay indicated the invasion was enhanced obviously by HE4 in ovarian cancer cells ES-2 and Caov-3 (panel B, P < 0.01, original magnification 40). Transwell assay indicated the metastasis capacities were enhanced by HE4 in ovarian cancer cells ES-2 and Caov-3 (panel C, P < 0.01, original magnification 200).