Abstract
Five hundred and fifty-two strains of Staphylococcus aureus of hospital origin were resistant to penicillin, streptomycin, and tetracycline. Of these, 298 were also resistant to neomycin and kanamycin, and this resistance was related to pigment production on glycerol monoacetate agar, the production of β-lysin, the absence of fibrinolytic and proteolytic activity, and to phage susceptibility. The use of physiological markers, the inadequacy of phage typing, and the possible reasons for the emergence of neomycin-resistant staphylococci are discussed.
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Selected References
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- COHEN L. S., FEKETY F. R., CLUFF L. E. Studies of the epidemiology of staphylococcal infection. IV. The changing ecology of hospital staphylococci. N Engl J Med. 1962 Feb 22;266:367–372. doi: 10.1056/NEJM196202222660801. [DOI] [PubMed] [Google Scholar]
- JACOBS S. I., WILLIS A. T., GOODBURN G. M. PIGMENT PRODUCTION AND ENZYMATIC ACTIVITY OF STAPHYLOCOCCI: THE DIFFERENTIATION OF PATHOGENS FROM COMMENSALS. J Pathol Bacteriol. 1964 Jan;87:151–156. doi: 10.1002/path.1700870121. [DOI] [PubMed] [Google Scholar]
- JACOBS S. I., WILLIS A. T. NEOMYCIN RESISTANCE IN NEWLY RECOGNISED STRAINS OF STAPHYLOCOCCUS AUREUS. Lancet. 1963 Aug 31;2(7305):459–460. doi: 10.1016/s0140-6736(63)92197-4. [DOI] [PubMed] [Google Scholar]
- JACOBS S. I., WILLLIS A. T., LUDLAM G. B., GOODBURN G. M. Studies on newly recognised strains of Staphylococcus aureus associated with hospital infection. Lancet. 1963 May 4;1(7288):972–973. doi: 10.1016/s0140-6736(63)91752-5. [DOI] [PubMed] [Google Scholar]
- KUNIN C. M., WILCOX C., NAJARIAN A., FINLAND M. Susceptibility and crossresistance of bacteria to four related antibiotics: kanamycin, paromomycin, neomycin and streptomycin. Proc Soc Exp Biol Med. 1958 Nov;99(2):312–316. doi: 10.3181/00379727-99-24334. [DOI] [PubMed] [Google Scholar]
- ROBERTSON J. J. NEOMYCIN RESISTANCE IN A NEWLY RECOGNIZED STAIN OF STAPHYLOCOCCUS AUREUS. Lancet. 1963 Aug 17;2(7303):333–334. doi: 10.1016/s0140-6736(63)92996-9. [DOI] [PubMed] [Google Scholar]
- TEMPLE N. E., BLACKBURN E. A. A newly recognised strain of Staphylococcus aureus associated with epidemics in six hospitals. Lancet. 1963 Mar 16;1(7281):581–583. doi: 10.1016/s0140-6736(63)92690-4. [DOI] [PubMed] [Google Scholar]
- WILLIS A. T., JACOBS S. I., GOODBURN G. M. Observations on multiple-antibiotic-resistant epidemic strains of Staphylococcus aureus. Lancet. 1963 Jul 13;2(7298):67–68. doi: 10.1016/s0140-6736(63)90065-5. [DOI] [PubMed] [Google Scholar]
