Table 1. Least square means, standard deviations, and 95% confidence intervals for general and neuropsychiatric characteristics classified by diagnostic group. (n=46).
| Mean ± SD [95% CI] |
bvFTD (N = 15) |
svPPA (N = 7) |
AD (N = 12) |
NC (N= 12) |
F | P-value | η2 |
|---|---|---|---|---|---|---|---|
| Gender: (M/F) |
12/3 | 5/2 | 5/7 | 6/6 | χ2 = 5.1 | .17 | V=.19 |
| Age: | 61.5±8.3 [57.3, 65.7] |
62.4±8.2 [56.3, 68.6] |
57.8±6.4 [53.1,62.5] |
65.7±9.2 [59.5, 69.7] |
1.89 | .27 | .09 |
| Education: | 17.1±2.4 [15.8, 18.5] |
17±3.3 [15, 19] |
14.9±2.8 [13.4, 16.4] |
17.8±2.1 [16.3, 19.5] |
2.83 | .05 | .18 |
| MMSE Total (max 30): | 24.5±5 [21.9,27.0] * |
19.4±7 [15.7,23.2] * |
21.4±5.7 [18.6,24.3] * |
29.6±0.8 [26.7, 32.5] |
26.11 | <.001 | .37 |
| CDR Total: | 1.1±0.5 [0.9, 1.4] * |
0.7±0.6 [0.5, 1.2] * |
0.8±0.5 [0.6, 1.1] * |
0±0 [-0.3, 0.3] |
8.29 | <.001 | .50 |
| Boxscore: | 6.8±2.2 [5.8, 7.9] * |
4.7±2.3 [3.2, 6.3] * |
4.7±2.3 [3.5,5.9] * |
0±0 [1.4, 1.4] |
7.91 | <.001 | .62 |
| NPI: | 41.9±21.5 [34, 49.8] * |
36.3±20.9 [24.7, 47.8] * |
9.1±6.4 [-0.5, 17.1] * |
0±0 [-8.82, 8.8] |
18.56 | <.001 | .46 |
Group effects were analyzed using glms with post-hoc Dunett-Hsu tests;
*
p < 0.05 compared to normal controls.
Abbreviations: SD=standard deviation; CI=confidence interval; AD = Alzheimer's dementia, bvFTD = behavioral variant frontotemporal dementia, svPPA = semantic variant primary progressive aphasia, NC = Normal Controls; MMSE= Mini-Mental State Examination; CRD = Clinical Dementia Rating; NPI = Neuropsychiatric Inventory