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. 2016 Feb 24;8(1):5. doi: 10.3390/pharmaceutics8010005

Figure 2.

Figure 2

Induction assay. Concentration-dependent effect of venetoclax (0.01–10 µM) and 20 µM of rifampicin (positive control for PXR-driven genes) after four days on mRNA expression in LS180 cells compared to untreated medium control. Expression data were normalized to the housekeeping gene β2mg. Data are expressed as mean ± SEM for n = 5 biological replicates and normalized to the medium control (set to 1). Differences in mRNA expression to the medium control were tested using ANOVA with Dunnett’s post hoc test. * p < 0.05, ** p < 0.01.