Abstract
Scintigraphic examination of the myocardium, using 99mTc-labelled pyrophosphate, was carried out in 17 patients suffering from systemic sclerosis. This connective tissue disorder very often affects the myocardium secondarily. The results of the cardiac scan were compared with the information obtained from the electrocardiogram of systolic time intervals. In addition, spirometry was undertaken to detect a potential relation between cardiac and pulmonary involvement. The scan was found to be positive in seven patients and electrocardiographic findings were pathological in five patients only. The systolic time intervals were abnormal in three patients only. A ventilation disturbance was recorded in 10 patients. No clear relation was found between the results of the individual examinations. It is concluded that pyrophosphate heart scintigraphy may detect myocardial impairment in some cases of systemic sclerosis before it is manifested by heart failure. Examination of systolic time intervals is of little importance.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buja L. M., Parkey R. W., Stokely E. M., Bonte F. J., Willerson J. T. Pathophysiology of technetium-99m stannous pyrophosphate and thallium-201 scintigraphy of acute anterior myocardial infarcts in dogs. J Clin Invest. 1976 Jun;57(6):1508–1522. doi: 10.1172/JCI108421. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Davison R., Spies S. M., Przybylek J., Hai H., Lesch M. Technetium-99m stannous pyrophosphate myocardial scintigraphy after cardiopulmonary resuscitation with cardioversion. Circulation. 1979 Aug;60(2):292–296. doi: 10.1161/01.cir.60.2.292. [DOI] [PubMed] [Google Scholar]
- Duska F., Vizda J., Kubícek J., Kafka P., Nesvadba Z., Zdánský P., Bastecký J. The sensitivity of scintigraphic myocardial imaging by the use of 99mTc-labelled pyrophosphate in the diagnosis of cardiomyopathy of various etiology. Eur J Nucl Med. 1979 Apr 1;4(2):87–90. doi: 10.1007/BF00626076. [DOI] [PubMed] [Google Scholar]
- Dymond D. S., Jarritt P. H., Britton K. E., Langley D., Spurrell R. A. Positive myocardial scintigraphy at the bedside--evaluation using a portable gamma camera. Postgrad Med J. 1978 Oct;54(636):641–648. doi: 10.1136/pgmj.54.636.641. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parkey R. W., Bonte F. J., Meyer S. L., Atkins J. M., Curry G. L., Stokely E. M., Willerson J. T. A new method for radionuclide imaging of acute myocardial infarction in humans. Circulation. 1974 Sep;50(3):540–546. doi: 10.1161/01.cir.50.3.540. [DOI] [PubMed] [Google Scholar]
- Perez L. A., Hayt D. B., Freeman L. M. Localization of myocardial disorders other than infarction with 99mTc-labeled phosphate agents. J Nucl Med. 1976 Apr;17(4):241–246. [PubMed] [Google Scholar]
- Wald R. W., Sternberg L., Huckell V. F., Staniloff H. M., Feiglin D. H., Morch J. E. Technetium-99m stannous pyrophosphate scintigraphy in patients with calcification within the cardiac silhouette. Br Heart J. 1978 May;40(5):547–551. doi: 10.1136/hrt.40.5.547. [DOI] [PMC free article] [PubMed] [Google Scholar]