Table 3. Rev-GFP values correlate to XPO1 occupancy values in MM.1S cells treated with different SINE compounds.

SINE Compound	Rev-GFP IC50 (μM)	Avg 50% Occupancy (μM)	Avg 90% Occupancy (μM)
Verdinexor	0.01	0.04 +/− 0.03 (n = 3)	0.34 +/− 0.08 (n = 3)
KPT-8602	0.04	0.06 +/− 0.06 (n = 2)	1.1 +/− 1.03 (n = 2)
Selinexor	0.04	0.08 +/− 0.01 (n = 2)	0.52 +/− 0.05 (n = 2)
KPT-350	0.17	0.63 +/− 0.29 (n = 3)	6.45 +/− 3.36 (n = 3)