There is an error in Table 1, in the variable “Pharmacological treatment for depression.” The corresponding chi-square value is indicated as χ = 103.96, but it should read χ2 = 103.96.
Table 1. Overview of the baseline characteristics of the cohort.
The summary statistics (mean and standard deviation) or the frequency distribution of each variable are shown in the overall population and by the presence/absence of clinically relevant depressive symptoms (GDS≥5 vs GDS<5).The statistical tests and p-values relative to analyses by GDS categories are also reported.
| Overall population | GDS < 5(n = 1069) | GDS ≥ 5(n = 200) | Test and p-value | |||
|---|---|---|---|---|---|---|
| Gender (n = 1321) | Female, n (%) | 714 (54.05) | 529 (49.49) | 157 (78.50) | χ2 = 57.11, p < .001 | |
| male, n (%) | 607 (45.95) | 540 (50.51) | 43 (21.50) | |||
| Age in years (n = 1321), mean ± SD | 72.04±1.45 | 71.96±1.45 | 72.35±1.43 | t = -3.49, p = .0005 | ||
| Marital status (n = 1319) | coupled, n (%) | 885 (67.1) | 743 (69.50) | 116 (58.00) | χ2 = 19.91, p < .001 | |
| single, n (%) | 80 (6.07) | 66 (6.17) | 6 (3.00) | |||
| uncoupled, n (%) | 354 (26.84) | 260 (24.32) | 78 (39.00) | |||
| Years of education (n = 1319), mean ± SD | 6.76±3.35 | 6.84±3.31 | 6.66±3.31 | t = 0.71, p = .48 | ||
| Number of adverse life events (n = 1297), mean ± SD | 1.98±1.33 | 1.90±1.31 | 2.45±1.39 | t = -5.39, p < .0001 | ||
| 5-HTTLPR (n = 1312) | LL, n (%) | 423 (32.24) | 347 (32.61) | 59 (29.50) | χ2 = 4.67, p = .10 | |
| LS, n (%) | 649 (49.47) | 535 (50.18) | 94 (47.00) | |||
| SS, n (%) | 240 (18.29) | 182 (17.11) | 47 (23.50) | |||
| rs25531 (n = 1312) | AA, n (%) | 1168 (89.02) | 955 (89.76) | 171 (85.50) | χ2 = 7.85, p = .02 | |
| AG, n (%) | 143 (10.90) | 109 (10.24) | 28 (14.00) | |||
| GG, n (%) | 1 (0.08) | 0 (0) | 1 (0.50) | |||
| 5HTTLPR-rs25531 (n = 1312) | L′L′, n (%) | 344 (26.22) | 290 (27.26) | 41 (20.50) | χ2 = 7.17, p = .03 | |
| L′S′, n (%) | 663 (50.53) | 541 (50.85) | 100 (50.00) | |||
| S′S′, n (%) | 305 (23.25) | 233 (21.90) | 59 (29.50) | |||
| History of depression (n = 1260) | positive, n (%) | 292 (23.17) | 167 (16.14) | 114 (61.96) | χ2 = 184.92, p < .001 | |
| negative, n (%) | 968 (76.83) | 868 (83.86) | 70 (38.04) | |||
| Pharmacological treatment for depression (n = 1309) | no treatment, n (%) | 1027 (78.46) | 891 (83.43) | 108 (54.00) | χ2 = 103.96, p < .001 | |
| anxiolytic treatment, n (%) | 174 (13.29) | 123 (11.52) | 46 (23.00) | |||
| antidepressant treatment, n (%) | 108 (8.25) | 54 (5.06) | 46 (23.00) | |||
| Comorbidity Index (n = 1309), score mean ± SD | 2.27±1.53 | 2.12±1.42 | 2.82±1.72 | t = -6.14, p < .001 | ||
There is an error in the Acknowledgments section. It should read: The authors are grateful to “Federazione Alzheimer Italia”, Milan, for overseeing the recruitment phase and the correct execution of the InveCe.Ab study and also acknowledge Valeria Marzagalli, Golgi Cenci Foundation, Abbiategrasso, for her contribution to the data collection and quality control.
Reference
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