Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1983 Feb;49(2):183–186. doi: 10.1136/hrt.49.2.183

Effect of hydration state on cardiac function in patients on chronic haemodialysis.

S Golf, P Lunde, A M Abrahamsen, A Oyri
PMCID: PMC481283  PMID: 6824541

Abstract

Haemodynamic studies were performed at rest and during exercise in five chronic haemodialysis patients at two different states of hydration, called "normal hydration" and "over-hydration" (mean change in body weight 2.9 kg). Apart from an increase in mean aortic pressure and cardiac index there were no signs of cardiac dysfunction at rest at normal hydration. On exercise the mean pulmonary artery and wedge pressure increased significantly while cardiac output doubled. Overhydration caused considerable increases in right and left sided heart pressures at rest, without any increase in cardiac index. These changes became more pronounced during exercise. Anaemia and arteriovenous shunting make dialysis patients very sensitive to volume load. Extreme anaemia should be avoided, and keeping dialysis patients in a state of low volume load should be given high priority.

Full text

PDF
183

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azancot I., Degoulet P., Juillet Y., Rottembourg J., Legrain M. Hemodynamic evaluation of hypotension during chronic hemodialysis. Clin Nephrol. 1977 Jul;8(1):312–316. [PubMed] [Google Scholar]
  2. Brass H., Krückels E. D., Müller G., Heintz R. Pathomechanismen der Herzinsuffizienz bei Hämodialysepatienten. Dtsch Med Wochenschr. 1971 Aug;96(33):1319–1324. doi: 10.1055/s-0028-1110133. [DOI] [PubMed] [Google Scholar]
  3. Capelli J. P., Kasparian H. Cardiac work demands and left ventricular function in end-stage renal disease. Ann Intern Med. 1977 Mar;86(3):261–267. doi: 10.7326/0003-4819-86-3-261. [DOI] [PubMed] [Google Scholar]
  4. Del Greco F., Simon N. M., Roguska J., Walker C. Hemodynamic studies in chronic uremia. Circulation. 1969 Jul;40(1):87–95. doi: 10.1161/01.cir.40.1.87. [DOI] [PubMed] [Google Scholar]
  5. Dongradi G., Rocha P., Baron B., Khazine F., Simons O., Kahn J. C., Fendler J. P. Hemodynamic effects of arteriovenous fistulae in chronic hemodialysis patients at rest and during exercise. Clin Nephrol. 1981 Feb;15(2):75–79. [PubMed] [Google Scholar]
  6. Drüeke T., Le Pailleur C., Meilhac B., Koutoudis C., Zingraff J., Di Matteo J., Crosnier J. Congestive cardiomyopathy in uraemic patients on long term haemodialysis. Br Med J. 1977 Feb 5;1(6057):350–353. doi: 10.1136/bmj.1.6057.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Endou K., Kamijima J., Kakubari Y., Kikawada R. Hemodynamic changes during hemodialysis. Cardiology. 1978;63(3):175–187. doi: 10.1159/000169895. [DOI] [PubMed] [Google Scholar]
  8. Hampl H., Paeprer H., Unger V., Kessel M. W. Hemodynamics during hemodialysis, sequential ultrafiltration and hemofiltration. J Dial. 1979;3(1):51–71. doi: 10.3109/08860227909064912. [DOI] [PubMed] [Google Scholar]
  9. Lakier J. B., Levin N. W. Cardiovascular effects of the hemodialysis procedure. Int J Artif Organs. 1981 Jan;4(1):4–7. [PubMed] [Google Scholar]
  10. Lazarus J. M., Lowrie E. G., Hampers C. L., Merrill J. P. Cardiovascular disease in uremic patients on hemodialysis. Kidney Int Suppl. 1975 Jan;(2):167–175. [PubMed] [Google Scholar]
  11. Macdonald I. L., Uldall R., Buda A. J. The effect of hemodialysis on cardiac rhythm and performance. Clin Nephrol. 1981 Jun;15(6):321–327. [PubMed] [Google Scholar]
  12. Neff M. S., Kim K. E., Persoff M., Onesti G., Swartz C. Hemodynamics of uremic anemia. Circulation. 1971 Jun;43(6):876–883. doi: 10.1161/01.cir.43.6.876. [DOI] [PubMed] [Google Scholar]
  13. Onesti G., Kim K. E., Greco J. A., del Guercio E. T., Fernandes M., Swartz C. Blood pressure regulation in end-stage renal disease and anephric man. Circ Res. 1975 Jun;36(6 Suppl 1):145–152. doi: 10.1161/01.res.36.6.145. [DOI] [PubMed] [Google Scholar]
  14. Wehle B., Asaba H., Castenfors J., Fürst P., Gunnarsson B., Shaldon S., Bergström J. Hemodynamic changes during sequential ultrafiltration and dialysis. Kidney Int. 1979 Apr;15(4):411–418. doi: 10.1038/ki.1979.53. [DOI] [PubMed] [Google Scholar]
  15. Weissler A. M., Harris W. S., Schoenfeld C. D. Bedside technics for the evaluation of ventricular function in man. Am J Cardiol. 1969 Apr;23(4):577–583. doi: 10.1016/0002-9149(69)90012-5. [DOI] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES