Skip to main content
British Heart Journal logoLink to British Heart Journal
. 1983 Jun;49(6):528–531. doi: 10.1136/hrt.49.6.528

Plasma vasopressin and blood pressure. Studies in normal subjects and in benign essential hypertension at rest and after postural challenge.

R Davies, M Forsling, G Bulger, T Phillips
PMCID: PMC481345  PMID: 6849715

Abstract

Plasma vasopressin levels were compared in three groups comprising normotensive, mildly hypertensive, and more severely hypertensive patients, both under basal conditions and following an 85 degrees head-up tilt, a stimulus known to provoke vasopressin release in man. Vasopressin levels increased two- to fivefold in all subjects after tilt; however, neither the basal levels nor the maximal levels attained at 45 to 60 minutes after tilt differed in the three groups. These data do not support the postulated role for vasopressin in the causation or perpetuation of non-accelerated essential hypertension in man.

Full text

PDF
528

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cochrane J. P., Forsling M. L., Gow N. M., Le Quesne L. P. Arginine vasopressin release following surgical operations. Br J Surg. 1981 Mar;68(3):209–213. doi: 10.1002/bjs.1800680322. [DOI] [PubMed] [Google Scholar]
  2. Davies R., Slater J. D., Forsling M. L., Payne N. The response of arginine vasopressin and plasma renin to postural change in normal man, with observations on syncope. Clin Sci Mol Med. 1976 Sep;51(3):267–274. doi: 10.1042/cs0510267. [DOI] [PubMed] [Google Scholar]
  3. Karonen S. L., Mörsky P., Siren M., Seuderling U. An enzymatic solid-phase method for trace iodination of proteins and peptides with 125-iodine. Anal Biochem. 1975 Jul;67(1):1–10. doi: 10.1016/0003-2697(75)90266-3. [DOI] [PubMed] [Google Scholar]
  4. McMichael J., Sharpey-Schafer E. P. CARDIAC OUTPUT IN MAN BY A DIRECT FICK METHOD: Effects of Posture, Venous Pressure Change, Atropine, And Adrenaline. Br Heart J. 1944 Jan;6(1):33–40. doi: 10.1136/hrt.6.1.33. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Möhring J., Möhring B., Petri M., Haack D. Is vasopressin involved in the pathogenesis of malignant desoxycorticosterone hypertension in rats? Lancet. 1976 Jan 24;1(7952):170–173. doi: 10.1016/s0140-6736(76)91275-7. [DOI] [PubMed] [Google Scholar]
  6. Möhring J., Möhring B., Petri M., Haack D. Plasma vasopressin concentrations and effects of vasopressin antiserum on blood pressure in rats with malignant two-kidney Goldblatt hypertension. Circ Res. 1978 Jan;42(1):17–22. doi: 10.1161/01.res.42.1.17. [DOI] [PubMed] [Google Scholar]
  7. Möhring J., Möhring B., Petri M., Haack D. Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension. Am J Physiol. 1977 Mar;232(3):F260–F269. doi: 10.1152/ajprenal.1977.232.3.F260. [DOI] [PubMed] [Google Scholar]
  8. Oliver G., Schäfer E. A. On the Physiological Action of Extracts of Pituitary Body and certain other Glandular Organs: Preliminary Communication. J Physiol. 1895 Jul 18;18(3):277–279. doi: 10.1113/jphysiol.1895.sp000565. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Padfield P. L., Brown J. J., Lever A. F., Morton J. J., Robertson J. I. Changes of vasopressin in hypertension: Cause or effect? Lancet. 1976 Jun 12;1(7972):1255–1257. doi: 10.1016/s0140-6736(76)91734-7. [DOI] [PubMed] [Google Scholar]
  10. Philipp T., Distler A., Cordes U. Sympathetic nervous system and blood-pressure control in essential hypertension. Lancet. 1978 Nov 4;2(8097):959–963. doi: 10.1016/s0140-6736(78)92526-6. [DOI] [PubMed] [Google Scholar]
  11. Rogge J. D., Moore W. W. Influence of lower body negative pressure on peripheral venous ADH levels in man. J Appl Physiol. 1968 Aug;25(2):134–138. doi: 10.1152/jappl.1968.25.2.134. [DOI] [PubMed] [Google Scholar]
  12. Skowsky W. R., Rosenbloom A. A., Fisher D. A. Radioimmunoassay measurement of arginine vasopressin in serum: development and application. J Clin Endocrinol Metab. 1974 Feb;38(2):278–287. doi: 10.1210/jcem-38-2-278. [DOI] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES