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. 1983 Dec;50(6):530–533. doi: 10.1136/hrt.50.6.530

Hypertrophic cardiomyopathy: a common disease with a good prognosis. Five year experience of a district general hospital.

L M Shapiro, A Zezulka
PMCID: PMC481455  PMID: 6686058

Abstract

The manifestations and workload in a district general hospital cardiac unit of 39 unselected cases of hypertrophic cardiomyopathy over a five year period are reported. The "typical" form with asymmetrical septal hypertrophy and a gradient was found in only one third of patients, serious ventricular arrhythmias were probably no more common than in the general population, and no deaths occurred during a relatively short follow up (mean 3.1 years). It is concluded that although hypertrophic cardiomyopathy occupies a not insignificant proportion of cardiac workload, unselected cases presenting to a district general hospital represent a relatively mild disease without a grave prognosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BROCK R. Functional obstruction of the left ventricle; acquired aortic subvalvar stenosis. Guys Hosp Rep. 1957;106(4):221–238. [PubMed] [Google Scholar]
  2. Bjarnason I., Jonsson S., Hardarson T. Mode of inheritance of hypertrophic cardiomyopathy in Iceland. Echocardiographic study. Br Heart J. 1982 Feb;47(2):122–129. doi: 10.1136/hrt.47.2.122. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bulkley B. H. Idiopathic hypertrophic subaortic stenosis afflicted: idols of the cave and the marketplace. Am J Cardiol. 1977 Sep;40(3):476–479. doi: 10.1016/0002-9149(77)90176-x. [DOI] [PubMed] [Google Scholar]
  4. COHEN J., EFFAT H., GOODWIN J. F., OAKLEY C. M., STEINER R. E. HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY. Br Heart J. 1964 Jan;26:16–32. doi: 10.1136/hrt.26.1.16. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Clarke J. M., Hamer J., Shelton J. R., Taylor S., Venning G. R. The rhythm of the normal human heart. Lancet. 1976 Sep 4;1(7984):508–512. doi: 10.1016/s0140-6736(76)90801-1. [DOI] [PubMed] [Google Scholar]
  6. Davies M. J., Pomerance A., Teare R. D. Pathological features of hypertrophic obstructive cardiomyopathy. J Clin Pathol. 1974 Jul;27(7):529–535. doi: 10.1136/jcp.27.7.529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Doi Y. L., McKenna W. J., Gehrke J., Oakley C. M., Goodwin J. F. M mode echocardiography in hypertrophic cardiomyopathy: diagnostic criteria and prediction of obstruction. Am J Cardiol. 1980 Jan;45(1):6–14. doi: 10.1016/0002-9149(80)90213-1. [DOI] [PubMed] [Google Scholar]
  8. GOODWIN J. F., HOLLMAN A., CLELAND W. P., TEARE D. Obstructive cardiomyopathy simulating aortic stenosis. Br Heart J. 1960 Jun;22:403–414. doi: 10.1136/hrt.22.3.403. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Goodwin J. F. Hypertrophic cardiomyopathy: a disease in search of its own identity. Am J Cardiol. 1980 Jan;45(1):177–180. doi: 10.1016/0002-9149(80)90236-2. [DOI] [PubMed] [Google Scholar]
  10. Goodwin J. F. The frontiers of cardiomyopathy. Br Heart J. 1982 Jul;48(1):1–18. doi: 10.1136/hrt.48.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Maron B. J., Lipson L. C., Roberts W. C., Savage D. D., Epstein S. E. "Malignant" hypertrophic cardiomyopathy: identification of a subgroup of families with unusually frequent premature death. Am J Cardiol. 1978 Jun;41(7):1133–1140. doi: 10.1016/0002-9149(78)90870-6. [DOI] [PubMed] [Google Scholar]
  12. Maron B. J., Roberts W. C., Epstein S. E. Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation. 1982 Jun;65(7):1388–1394. doi: 10.1161/01.cir.65.7.1388. [DOI] [PubMed] [Google Scholar]
  13. McKenna W. J., England D., Doi Y. L., Deanfield J. E., Oakley C., Goodwin J. F. Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis. Br Heart J. 1981 Aug;46(2):168–172. doi: 10.1136/hrt.46.2.168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. McKenna W., Deanfield J., Faruqui A., England D., Oakley C., Goodwin J. Prognosis in hypertrophic cardiomyopathy: role of age and clinical, electrocardiographic and hemodynamic features. Am J Cardiol. 1981 Mar;47(3):532–538. doi: 10.1016/0002-9149(81)90535-x. [DOI] [PubMed] [Google Scholar]
  15. Ryan M., Lown B., Horn H. Comparison of ventricular ectopic activity during 24-hour monitoring and exercise testing in patients with coronary heart disease. N Engl J Med. 1975 Jan 30;292(5):224–229. doi: 10.1056/NEJM197501302920502. [DOI] [PubMed] [Google Scholar]
  16. Savage D. D., Seides S. F., Maron B. J., Myers D. J., Epstein S. E. Prevalence of arrhythmias during 24-hour electrocardiographic monitoring and exercise testing in patients with obstructive and nonobstructive hypertrophic cardiomyopathy. Circulation. 1979 May;59(5):866–875. doi: 10.1161/01.cir.59.5.866. [DOI] [PubMed] [Google Scholar]
  17. Shapiro L. M., McKenna W. J. Distribution of left ventricular hypertrophy in hypertrophic cardiomyopathy: a two-dimensional echocardiographic study. J Am Coll Cardiol. 1983 Sep;2(3):437–444. doi: 10.1016/s0735-1097(83)80269-1. [DOI] [PubMed] [Google Scholar]
  18. Simon A. L., Ross J., Jr, Gault J. H. Angiographic anatomy of the left ventricle and mitral valve in idiopathic hypertrophic subaortic stenosis. Circulation. 1967 Dec;36(6):852–867. doi: 10.1161/01.cir.36.6.852. [DOI] [PubMed] [Google Scholar]
  19. TEARE D. Asymmetrical hypertrophy of the heart in young adults. Br Heart J. 1958 Jan;20(1):1–8. doi: 10.1136/hrt.20.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Whiting R. B., Powell W. J., Jr, Dinsmore R. E., Sanders C. A. Idiopathic hypertrophic subaortic stenosis in the elderly. N Engl J Med. 1971 Jul 22;285(4):196–200. doi: 10.1056/NEJM197107222850404. [DOI] [PubMed] [Google Scholar]
  21. Yamaguchi H., Ishimura T., Nishiyama S., Nagasaki F., Nakanishi S., Takatsu F., Nishijo T., Umeda T., Machii K. Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): ventriculographic and echocardiographic features in 30 patients. Am J Cardiol. 1979 Sep;44(3):401–412. doi: 10.1016/0002-9149(79)90388-6. [DOI] [PubMed] [Google Scholar]

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