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Epigenetic modifications occurring during spermatogenesis. DNA methylation occurs in mitotic germ cells, setting up the paternal specific imprints. Phosphorylation occurs in meiotic cells, assisting in both recombination and XY body formation. Ubiquitylation, sumoylation, and incorporation of the H2AZ and H3.3 variants are all involved in XY body formation. During spermiogenesis, hyperacetylation occurs to assist in the histone-protamine transition.
