Abstract
To evaluate the usefulness and accuracy of calculating left ventricular volume and ejection fraction from cross sectional echocardiograms in patients with tetralogy of Fallot, 28 patients were studied within 24 hours of cineangiography. Indexed end diastolic and end systolic volumes were calculated from three different paired echocardiographic projections: (a) the two and four chamber views from the apical impulse window, (b) the parasternal long axis view and the subxiphoid long axis view, and (c) the four chamber view and short axis precordial views at mitral and papillary muscle level. Volumes were calculated in five different ways using three different algorithms (area length, Simpson's rule, the Parisi formula). The results were compared with data obtained from biplane angiograms using Graham's formula. The correlation varied with the algorithm used: the best results were obtained with the area length method using the parasternal long axis view and the sub-xiphoid view. The correlation was less accurate for the ejection fraction. The second best correlation was obtained with the area length method using the two and four chamber apical views; the other correlations were less satisfactory. Thus these results show that left ventricular volumes can be accurately assessed by cross sectional echocardiography in children with tetralogy of Fallot and that the ejection fraction can be satisfactorily estimated. The results depend on careful gain setting and precise demonstration of the left ventricular endocardium, which is best seen in the sub-xiphoid and long axis views.
Full text
PDF






Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bhatt D. R., Isabel-Jones J. B., Villoria G. J., Nakazawa M., Yabek S. M., Marks R. A., Jarmakani J. M. Accuracy of echocardiography in assessing left ventricular dimensions and volume. Circulation. 1978 Apr;57(4):699–707. doi: 10.1161/01.cir.57.4.699. [DOI] [PubMed] [Google Scholar]
- Bierman F. Z., Williams R. G. Subxiphoid two-dimensional imaging of the interatrial septum in infants and neonates with congenital heart disease. Circulation. 1979 Jul;60(1):80–90. doi: 10.1161/01.cir.60.1.80. [DOI] [PubMed] [Google Scholar]
- Carr K. W., Engler R. L., Forsythe J. R., Johnson A. D., Gosink B. Measurement of left ventricular ejection fraction by mechanical cross-sectional echocardiography. Circulation. 1979 Jun;59(6):1196–1206. doi: 10.1161/01.cir.59.6.1196. [DOI] [PubMed] [Google Scholar]
- DODGE H. T., SANDLER H., BALLEW D. W., LORD J. D., Jr The use of biplane angiocardigraphy for the measurement of left ventricular volume in man. Am Heart J. 1960 Nov;60:762–776. doi: 10.1016/0002-8703(60)90359-8. [DOI] [PubMed] [Google Scholar]
- Eaton L. W., Maughan W. L., Shoukas A. A., Weiss J. L. Accurate volume determination in the isolated ejecting canine left ventricle by two-dimensional echocardiography. Circulation. 1979 Aug;60(2):320–326. doi: 10.1161/01.cir.60.2.320. [DOI] [PubMed] [Google Scholar]
- Erbel R., Krebs W., Henn G., Schweizer P., Richter H. A., Meyer J., Effert S. Comparison of single-plane and biplane volume determination by two-dimensional echocardiography. 1. Asymmetric model hearts. Eur Heart J. 1982 Oct;3(5):469–480. doi: 10.1093/oxfordjournals.eurheartj.a061334. [DOI] [PubMed] [Google Scholar]
- Erbel R., Schweizer P., Meyer J., Grenner H., Krebs W., Effert S. Left ventricular volume and ejection fraction determination by cross-sectional echocardiography in patients with coronary artery disease: a prospective study. Clin Cardiol. 1980 Dec;3(6):377–383. doi: 10.1002/clc.4960030604. [DOI] [PubMed] [Google Scholar]
- Feigenbaum H., Popp R. L., Wolfe S. B., Troy B. L., Pombo J. F., Haine C. L., Dodge H. T. Ultrasound measurements of the left ventricle. A correlative study with angiocardiography. Arch Intern Med. 1972 Mar;129(3):461–467. [PubMed] [Google Scholar]
- Folland E. D., Parisi A. F., Moynihan P. F., Jones D. R., Feldman C. L., Tow D. E. Assessment of left ventricular ejection fraction and volumes by real-time, two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques. Circulation. 1979 Oct;60(4):760–766. doi: 10.1161/01.cir.60.4.760. [DOI] [PubMed] [Google Scholar]
- Gehrke J., Leeman S., Raphael M., Pridie R. B. Non-invasive left ventricular volume determination by two-dimensional echocardiography. Br Heart J. 1975 Sep;37(9):911–916. doi: 10.1136/hrt.37.9.911. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Geiser E. A., Skorton D. J., Conetta D. A. Quantification of left ventricular function by two-dimensional echocardiography: consideration of factors restricting image quality. Am Heart J. 1982 May;103(5):905–910. doi: 10.1016/0002-8703(82)90406-9. [DOI] [PubMed] [Google Scholar]
- Gibson D. G. Estimation of left ventricular size by echocardiography. Br Heart J. 1973 Feb;35(2):128–134. doi: 10.1136/hrt.35.2.128. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Graham T. P., Jr, Jarmakani J. M., Canent R. V., Jr, Morrow M. N. Left heart volume estimation in infancy and childhood. Reevaluation of methodology and normal values. Circulation. 1971 Jun;43(6):895–904. doi: 10.1161/01.cir.43.6.895. [DOI] [PubMed] [Google Scholar]
- Gueret P., Meerbaum S., Wyatt H. L., Uchiyama T., Lang T. W., Corday E. Two-dimensional echocardiographic quantitation of left ventricular volumes and ejection fraction. Importance of accounting for dyssynergy in short-axis reconstruction models. Circulation. 1980 Dec;62(6):1308–1318. doi: 10.1161/01.cir.62.6.1308. [DOI] [PubMed] [Google Scholar]
- Henry W. L., Maron B. J., Griffith J. M. Cross-sectional echocardiography in the diagnosis of congenital heart disease. Identification of the relation of the ventricles and great arteries. Circulation. 1977 Aug;56(2):267–273. doi: 10.1161/01.cir.56.2.267. [DOI] [PubMed] [Google Scholar]
- Hiraishi S., DiSessa T. G., Jarmakani J. M., Nakanishi T., Isabel-Jones J. B., Friedman W. F. Two-dimensional echocardiographic assessment of right ventricular volume in children with congenital heart disease. Am J Cardiol. 1982 Dec;50(6):1368–1375. doi: 10.1016/0002-9149(82)90476-3. [DOI] [PubMed] [Google Scholar]
- Jarmakani J. M., Graham T. P., Jr, Canent R. V., Jr, Jewett P. H. Left heart function in children with tetralogy of Fallot before and after palliative or corrective surgery. Circulation. 1972 Sep;46(3):478–490. doi: 10.1161/01.cir.46.3.478. [DOI] [PubMed] [Google Scholar]
- Kaye H. H., Tynan M., Hunter S. Validity of echocardiographic estimates of left ventricular size and performance in infants and children. Br Heart J. 1975 Apr;37(4):371–375. doi: 10.1136/hrt.37.4.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
- King D. L., Jaffee C. C., Schmidt D. H., Ellis K. Left ventricular volume determination by cross-sectional cardiac ultrasonography. Radiology. 1972 Jul;104(1):201–202. doi: 10.1148/104.1.201. [DOI] [PubMed] [Google Scholar]
- Krebs W., Erbel R., Schweizer P., Richter H. A., Henn G., Massberg I., Meyer J., Effert S. Volumenbestimmung des rechten Ventrikels mit Hilfe der Subtraktionsmethode-Eine vergleichende zweidimensionale echokardiographische und röntgenologische Studie an Herzmodellen. Z Kardiol. 1982 Jun;71(6):413–420. [PubMed] [Google Scholar]
- Lange P. E., Onnasch D. G., Schaupp G. H., Zill C., Heintzen P. H. Size and function of the human left and right ventricles during growth. Normative angiographic data. Pediatr Cardiol. 1982;3(3):205–211. doi: 10.1007/BF02240454. [DOI] [PubMed] [Google Scholar]
- Mercier J. C., DiSessa T. G., Jarmakani J. M., Nakanishi T., Hiraishi S., Isabel-Jones J., Friedman W. F. Two-dimensional echocardiographic assessment of left ventricular volumes and ejection fraction in children. Circulation. 1982 May;65(5):962–969. doi: 10.1161/01.cir.65.5.962. [DOI] [PubMed] [Google Scholar]
- Meyer R. A., Stockert J., Kaplan S. Echographic determination of left ventricular volumes in pediatric patients. Circulation. 1975 Feb;51(2):297–303. doi: 10.1161/01.cir.51.2.297. [DOI] [PubMed] [Google Scholar]
- Oberhänsli I., Friedli B. Echocardiographic study of right and left ventricular dimension and left ventricular function in patients with tetralogy of Fallot before and after surgery. Br Heart J. 1979 Jan;41(1):40–53. doi: 10.1136/hrt.41.1.40. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parisi A. F., Moynihan P. F., Feldman C. L., Folland E. D. Approaches to determination of left ventricular volume and ejection fraction by real-time two-dimensional echocardiography. Clin Cardiol. 1979 Aug;2(4):257–263. doi: 10.1002/clc.4960020404. [DOI] [PubMed] [Google Scholar]
- Schiller N. B., Acquatella H., Ports T. A., Drew D., Goerke J., Ringertz H., Silverman N. H., Brundage B., Botvinick E. H., Boswell R. Left ventricular volume from paired biplane two-dimensional echocardiography. Circulation. 1979 Sep;60(3):547–555. doi: 10.1161/01.cir.60.3.547. [DOI] [PubMed] [Google Scholar]
- Silverman N. H., Ports T. A., Snider A. R., Schiller N. B., Carlsson E., Heilbron D. C. Determination of left ventricular volume in children: echocardiographic and angiographic comparisons. Circulation. 1980 Sep;62(3):548–557. doi: 10.1161/01.cir.62.3.548. [DOI] [PubMed] [Google Scholar]
- Silverman N. H., Schiller N. B. Apex echocardiography. A two-dimensional technique for evaluating congenital heart disease. Circulation. 1978 Mar;57(3):503–511. doi: 10.1161/01.cir.57.3.503. [DOI] [PubMed] [Google Scholar]
- Sold G., Zwehl W., Vogt A., Kamp M., Neuhaus K. L., Kreuzer H. Bestimmung linksventrikulärer Volumina mittels zweidimensionaler Echokardiographie beim Hund: Korrelationen zur biplanen Angiokardiographie. Z Kardiol. 1981 May;70(5):357–363. [PubMed] [Google Scholar]
- Stamm R. B., Carabello B. A., Mayers D. L., Martin R. P. Two-dimensional echocardiographic measurement of left ventricular ejection fraction: prospective analysis of what constitutes an adequate determination. Am Heart J. 1982 Jul;104(1):136–144. doi: 10.1016/0002-8703(82)90651-2. [DOI] [PubMed] [Google Scholar]
- Tajik A. J., Seward J. B., Hagler D. J., Mair D. D., Lie J. T. Two-dimensional real-time ultrasonic imaging of the heart and great vessels. Technique, image orientation, structure identification, and validation. Mayo Clin Proc. 1978 May;53(5):271–303. [PubMed] [Google Scholar]
- Teichholz L. E., Kreulen T., Herman M. V., Gorlin R. Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. Am J Cardiol. 1976 Jan;37(1):7–11. doi: 10.1016/0002-9149(76)90491-4. [DOI] [PubMed] [Google Scholar]
- Wyatt H. L., Heng M. K., Meerbaum S., Gueret P., Hestenes J., Dula E., Corday E. Cross-sectional echocardiography. II. Analysis of mathematic models for quantifying volume of the formalin-fixed left ventricle. Circulation. 1980 Jun;61(6):1119–1125. doi: 10.1161/01.cir.61.6.1119. [DOI] [PubMed] [Google Scholar]
- Wyatt H. L., Heng M. K., Meerbaum S., Hestenes J. D., Cobo J. M., Davidson R. M., Corday E. Cross-sectional echocardiography. I. Analysis of mathematic models for quantifying mass of the left ventricle in dogs. Circulation. 1979 Nov;60(5):1104–1113. doi: 10.1161/01.cir.60.5.1104. [DOI] [PubMed] [Google Scholar]


