Abstract
Löffler's endocarditis is a recognised complication of diseases associated with eosinophilia. Eosinophilic heart disease is usually chronic, but there is a rare acute variety. Three patients with an unusual form of eosinophilic heart disease characterised by acute necrotising eosinophilic myocarditis after a possible initial viral infection and underlying allergic diathesis are reported. In contrast to previously reported cases of acute Löffler's endocarditis there was no notable extracardiac pathology.
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- BRINK A. J., WEBER H. W. Fibroplastic parietal endocarditis with eosinophilia. Loffler's endocarditis. Am J Med. 1963 Jan;34:52–70. doi: 10.1016/0002-9343(63)90038-x. [DOI] [PubMed] [Google Scholar]
- Baandrup U. Löffler's endocarditis and endomyocardial fibrosis--a nosologic entity? Acta Pathol Microbiol Scand A. 1977 Nov;85(6):869–874. doi: 10.1111/j.1699-0463.1977.tb03903.x. [DOI] [PubMed] [Google Scholar]
- Chusid M. J., Dale D. C., West B. C., Wolff S. M. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975 Jan;54(1):1–27. [PubMed] [Google Scholar]
- Davies J., Spry C. J., Sapsford R., Olsen E. G., de Perez G., Oakley C. M., Goodwin J. F. Cardiovascular features of 11 patients with eosinophilic endomyocardial disease. Q J Med. 1983 Winter;52(205):23–39. [PubMed] [Google Scholar]
- GARDIOL D., PICHT E. Encéphalopathie et myo-endocardite à éosinophiles; a propos d'un cas de tuberculose urogénital traité par des tuberculostatiques. Schweiz Z Tuberc Pneumonol. 1957;14(3):212–226. [PubMed] [Google Scholar]
- Gleich G. J., Frigas E., Loegering D. A., Wassom D. L., Steinmuller D. Cytotoxic properties of the eosinophil major basic protein. J Immunol. 1979 Dec;123(6):2925–2927. [PubMed] [Google Scholar]
- Gottdiener J. S., Maron B. J., Schooley R. T., Harley J. B., Roberts W. C., Fauci A. S. Two-dimensional echocardiographic assessment of the idiopathic hypereosinophilic syndrome. Anatomic basis of mitral regurgitation and peripheral embolization. Circulation. 1983 Mar;67(3):572–578. doi: 10.1161/01.cir.67.3.572. [DOI] [PubMed] [Google Scholar]
- Hardy W. R., Anderson R. E. The hypereosinophilic syndromes. Ann Intern Med. 1968 Jun;68(6):1220–1229. doi: 10.7326/0003-4819-68-6-1220. [DOI] [PubMed] [Google Scholar]
- Inoh T., Tsukitani M., Adachi Y., Motooka T., Fukuzaki H. A case of acute peri-myocarditis associated with delayed appearance of eosinophilia. Kobe J Med Sci. 1980 Dec;26(4):223–228. [PubMed] [Google Scholar]
- Lie J. T., Hunt D. Eosinophilic endomyocarditis complicating acute myocardial infarction. Involvement of the cardiac conduction system. Arch Intern Med. 1974 Oct;134(4):754–757. [PubMed] [Google Scholar]
- Mullick F. G., McAllister H. A. Myocarditis associated with methyldopa therapy. JAMA. 1977 Apr 18;237(16):1699–1701. [PubMed] [Google Scholar]
- Noren G. R., Staley N. A., Bandt C. M., Kaplan E. L. Occurrence of myocarditis in sudden death in children. J Forensic Sci. 1977 Jan;22(1):188–196. [PubMed] [Google Scholar]
- Oakley C. M., Olsen G. J. Eosinophilia and heart disease. Br Heart J. 1977 Mar;39(3):233–237. doi: 10.1136/hrt.39.3.233. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parrillo J. E., Borer J. S., Henry W. L., Wolff S. M., Fauci A. S. The cardiovascular manifestations of the hypereosinophilic syndrome. Prospective study of 26 patients, with review of the literature. Am J Med. 1979 Oct;67(4):572–582. doi: 10.1016/0002-9343(79)90227-4. [DOI] [PubMed] [Google Scholar]
- Popper H., Pongratz M., Lanzer G. IgA2-alveolitis and eosinophilic pneumonia--a possibly virus-triggered allergy. Allergol Immunopathol (Madr) 1982 May-Jun;10(3):177–184. [PubMed] [Google Scholar]
- Rasche R. F., Kelsch R. D., Weaver D. K. Löffler's endocarditis in childhood. Br Heart J. 1973 Jul;35(7):774–776. doi: 10.1136/hrt.35.7.774. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts W. C., Liegler D. G., Carbone P. P. Endomyocardial disease and eosinophilia. A clinical and pathologic spectrum. Am J Med. 1969 Jan;46(1):28–42. doi: 10.1016/0002-9343(69)90055-2. [DOI] [PubMed] [Google Scholar]
- Spry C. J., Davies J., Tai P. C., Olsen E. G., Oakley C. M., Goodwin J. F. Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med. 1983 Winter;52(205):1–22. [PubMed] [Google Scholar]
- Spry C. J., Tai P. C. Studies on blood eosinophils. II. Patients with Löffler's cardiomyopathy. Clin Exp Immunol. 1976 Jun;24(3):423–434. [PMC free article] [PubMed] [Google Scholar]
- Tai P. C., Hayes D. J., Clark J. B., Spry C. J. Toxic effects of human eosinophil products on isolated rat heart cells in vitro. Biochem J. 1982 Apr 15;204(1):75–80. doi: 10.1042/bj2040075. [DOI] [PMC free article] [PubMed] [Google Scholar]



