Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1985 Mar;53(3):337–340. doi: 10.1136/hrt.53.3.337

A complicated case of mitral valve disease.

S E James, R McKay, D N Ross
PMCID: PMC481765  PMID: 3970791

Abstract

A patient with rheumatic mitral stenosis and previous cerebral embolism had a myocardial infarction during cardiac catheterisation. She later developed severe mitral regurgitation one year after open valvotomy and at valve replacement was found to have a papillary tumour of the mitral valve. Unexplained low cardiac output occurred four days after operation. Postmortem examination showed thrombotic occlusion of the xenograft prosthesis, a complication not previously seen with tissue valves. Both of these rare events were suggested by the patient's clinical course and could have been diagnosed with cross sectional echocardiography.

Full text

PDF
337

Images in this article

338Image
on p.338
338Image
on p.338

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bennett E. V., Jr, Grover F. L., Trinkle J. K. Porcine valve bioprosthesis: early thrombosis with systemic emboli. Ann Thorac Surg. 1982 Feb;33(2):197–199. doi: 10.1016/s0003-4975(10)61910-8. [DOI] [PubMed] [Google Scholar]
  2. Butterworth J. S., Poindexter C. A. Papilloma of cusp of the aortic valve. Report of a patient with sudden death. Circulation. 1973 Jul;48(1):213–215. doi: 10.1161/01.cir.48.1.213. [DOI] [PubMed] [Google Scholar]
  3. Cha S. D., Incarvito J., Fernandez J., Chang K. S., Maranhao V., Gooch A. S. Giant Lambl's excrescences of papillary muscle and aortic valve: echocardiographic, angiographic, and pathologic findings. Clin Cardiol. 1981 Jan;4(1):51–54. doi: 10.1002/clc.4960040112. [DOI] [PubMed] [Google Scholar]
  4. Geha A. S., Hammond G. L., Laks H., Stansel H. C., Glenn W. W. Factors affecting performance and thromboembolism after porcine xenograft cardiac valve replacement. J Thorac Cardiovasc Surg. 1982 Mar;83(3):377–384. [PubMed] [Google Scholar]
  5. HARRIS L. S., ADELSON L. FATAL CORONARY EMBOLISM FROM A MYXOMATOUS POLYP OF THE AORTIC VALVE; AN UNUSUAL CAUSE OF SUDDEN DEATH. Am J Clin Pathol. 1965 Jan;43:61–64. doi: 10.1093/ajcp/43.1.61. [DOI] [PubMed] [Google Scholar]
  6. HEATH D., BEST P. V., DAVIS B. T. Papilliferous tumours of the heart valves. Br Heart J. 1961 Jan;23:20–24. doi: 10.1136/hrt.23.1.20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Heath D. Pathology of cardiac tumors. Am J Cardiol. 1968 Mar;21(3):315–327. doi: 10.1016/0002-9149(68)90136-7. [DOI] [PubMed] [Google Scholar]
  8. Hetzer R., Hill J. D., Kerth W. J., Wilson A. J., Adappa M. G., Gerbode F. Thrombosis and degeneration of Hancock valves: clinical and pathological findings. Ann Thorac Surg. 1978 Oct;26(4):317–322. doi: 10.1016/s0003-4975(10)62897-4. [DOI] [PubMed] [Google Scholar]
  9. Ishihara T., Ferrans V. J., Barnhart G. R., Jones M., McIntosh C. L., Roberts W. C. Intracuspal hematomas in implanted porcine valvular bioprostheses: clinical and experimental studies. J Thorac Cardiovasc Surg. 1982 Mar;83(3):399–407. [PubMed] [Google Scholar]
  10. Jamieson M. P., Bennett J. G., Robles A., Ross D. N. Clinical experience with the Carpentier-Edwards porcine xenograft. Thorac Cardiovasc Surg. 1981 Aug;29(4):200–205. doi: 10.1055/s-2007-1023477. [DOI] [PubMed] [Google Scholar]
  11. McComb R. D., Stahmann F. D., O'Connor W. N., Todd E. P. Structure-related thrombosis involving a porcine xenograft valve. Ann Thorac Surg. 1979 Feb;27(2):191–193. doi: 10.1016/s0003-4975(10)63268-7. [DOI] [PubMed] [Google Scholar]
  12. Nuñez L., Gil Aguado M., Larrea J. L., Celemín D., Oliver J. Prevention of thromboembolism using aspirin after mitral valve replacement with porcine bioprosthesis. Ann Thorac Surg. 1984 Jan;37(1):84–87. doi: 10.1016/s0003-4975(10)60717-5. [DOI] [PubMed] [Google Scholar]
  13. Ong L. S., Nanda N. C., Barold S. S. Two-dimensional echocardiographic detection and diagnostic features of left ventricular papillary fibroelastoma. Am Heart J. 1982 May;103(5):917–918. doi: 10.1016/0002-8703(82)90410-0. [DOI] [PubMed] [Google Scholar]
  14. POMERANCE A. Papillary "tumours" of the heart valves. J Pathol Bacteriol. 1961 Jan;81:135–140. doi: 10.1002/path.1700810116. [DOI] [PubMed] [Google Scholar]
  15. Platt M. R., Mills L. J., Estrera A. S., Hillis L. D., Buja L. M., Willerson J. T. Marked thrombosis and calcification of porcine heterograft valves. Circulation. 1980 Oct;62(4):862–869. doi: 10.1161/01.cir.62.4.862. [DOI] [PubMed] [Google Scholar]
  16. Salyer W. R., Page D. L., Hutchins G. M. The development of cardiac myxomas and papillary endocardial lesions from mural thrombus. Am Heart J. 1975 Jan;89(1):4–17. doi: 10.1016/0002-8703(75)90003-4. [DOI] [PubMed] [Google Scholar]
  17. Sands M. J., Jr, Lachman A. S., Leach C. N., Jr, Takata H., McLucas E. Thrombosis of the porcine heterograft heart valve bioprosthesis. Conn Med. 1981 Jan;45(1):7–11. [PubMed] [Google Scholar]
  18. Shub C., Tajik A. J., Seward J. B., Edwards W. D., Pruitt R. D., Orszulak T. A., Pluth J. R. Cardiac papillary fibroelastomas. Two-dimensional echocardiographic recognition. Mayo Clin Proc. 1981 Oct;56(10):629–633. [PubMed] [Google Scholar]
  19. St John Sutton M. G., Mercier L. A., Giuliani E. R., Lie J. T. Atrial myxomas: a review of clinical experience in 40 patients. Mayo Clin Proc. 1980 Jun;55(6):371–376. [PubMed] [Google Scholar]
  20. Stovin P. G., Heath D., Khaliq S. U. Ultrastructure of the cardiac myxoma and the papillary tumour of heart valves. Thorax. 1973 May;28(3):273–285. doi: 10.1136/thx.28.3.273. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Thiene G., Bortolotti U., Panizzon G., Milano A., Gallucci V. Pathological substrates of thrombus formation after heart valve replacement with the Hancock bioprosthesis. J Thorac Cardiovasc Surg. 1980 Sep;80(3):414–423. [PubMed] [Google Scholar]
  22. Wold L. E., Lie J. T. Cardiac myxomas: a clinicopathologic profile. Am J Pathol. 1980 Oct;101(1):219–240. [PMC free article] [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES