Skip to main content
NCBI home page
British Heart Journal logoLink to British Heart Journal
. 1985 Dec;54(6):577–582. doi: 10.1136/hrt.54.6.577

Preoperative and postoperative pulmonary function tests in patients with atrial septal defect and their relation to pulmonary artery pressure and pulmonary:systemic flow ratio.

P M Schofield, P V Barber, T Kingston
PMCID: PMC481955  PMID: 4074589

Abstract

Pulmonary diffusing properties and lung volumes were investigated in 44 patients with atrial septal defect, and in 30 of them preoperative and postoperative data were obtained. The patients were divided into three groups according to mean pulmonary artery pressure: less than or equal to 15 mm Hg (group 1), 16-29 mm Hg (group 2), and greater than or equal to 30 mm Hg (group 3). Patients in groups 1 and 2 had a high carbon monoxide transfer test which became normal after surgical correction of their septal defect. In group 3, the carbon monoxide transfer test was normal both before and after operation. As mean pulmonary artery pressure increased there was a progressive reduction in both forced expiratory volume in one second and vital capacity. Patients in group 3 had a low forced expiratory volume in one second, a low vital capacity, and a reduced forced expiratory volume in one second:vital capacity ratio. These abnormalities were not corrected by surgical closure of the septal defect. Formulas were derived from the lung function data, to predict the mean pulmonary artery pressure and the pulmonary:systemic flow ratio. The values predicted when these two formulas were applied to data obtained for patients in this study correlated well with measured values.

Full text

PDF
577

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AUCHINCLOSS J. H., Jr, GILBERT R., EICH R. H. The pulmonary diffusing capacity in congenital and rheumatic heart disease. Circulation. 1959 Feb;19(2):232–241. doi: 10.1161/01.cir.19.2.232. [DOI] [PubMed] [Google Scholar]
  2. BERGLUND E., BIRATH G., BJURE J., GRIMBY G., KJELLMER I., SANDQVIST L., SODERHOLM B. Spirometric studies in normal subjects. I. Forced expirograms in subjects between 7 and 70 years of age. Acta Med Scand. 1963 Feb;173:185–192. [PubMed] [Google Scholar]
  3. Bedell G. N., Adams R. W. PULMONARY DIFFUSING CAPACITY DURING REST AND EXERCISE. A STUDY OF NORMAL PERSONS AND PERSONS WITH ATRIAL SEPTAL DEFECT, PREGNANCY, AND PULMONARY DISEASE. J Clin Invest. 1962 Oct;41(10):1908–1914. doi: 10.1172/JCI104647. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bucci G., Cook C. D. STUDIES OF RESPIRATORY PHYSIOLOGY IN CHILDREN. VI. LUNG DIFFUSING CAPACITY, DIFFUSING CAPACITY OF THE PULMONARY MEMBRANE AND PULMONARY CAPILLARY BLOOD VOLUME IN CONGENITAL HEART DISEASE. J Clin Invest. 1961 Aug;40(8 Pt 1-2):1431–1441. doi: 10.1172/JCI104374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Burgess J. H. Pulmonary diffusing capacity in disorders of the pulmonary circulation. Circulation. 1974 Mar;49(3):541–550. doi: 10.1161/01.cir.49.3.541. [DOI] [PubMed] [Google Scholar]
  6. Danzer L. A., Cohn J. E., Zechman F. W. Relationship of Dm and Vc to pulmonary difusing capacity during exercise. Respir Physiol. 1968 Sep;5(2):250–258. doi: 10.1016/0034-5687(68)90063-7. [DOI] [PubMed] [Google Scholar]
  7. Dobbinson T. L., Gray I. G., Nisbet H. I., Pelton D. A., Levison H., Volgyesi G. Thoracic compliance and lung volumes in children with heart disease. Acta Anaesthesiol Scand. 1973;17(1):50–56. doi: 10.1111/j.1399-6576.1973.tb00797.x. [DOI] [PubMed] [Google Scholar]
  8. FLATLEY F. J., CONSTANTINE H., McCREDIE R. M., YU P. N. Pulmonary diffusing capacity and pulmonary capillary blood volume in normal subjects and in cardiac patients. Am Heart J. 1962 Aug;64:159–168. doi: 10.1016/0002-8703(62)90328-9. [DOI] [PubMed] [Google Scholar]
  9. Freed M. D., Nadas A. S., Norwood W. I., Castaneda A. R. Is routine preoperative cardiac catheterization necessary before repair of secundum and sinus venosus atrial septal defects? J Am Coll Cardiol. 1984 Aug;4(2):333–336. doi: 10.1016/s0735-1097(84)80222-3. [DOI] [PubMed] [Google Scholar]
  10. GOLDMAN H. I., BECKLAKE M. R. Respiratory function tests; normal values at median altitudes and the prediction of normal results. Am Rev Tuberc. 1959 Apr;79(4):457–467. doi: 10.1164/artpd.1959.79.4.457. [DOI] [PubMed] [Google Scholar]
  11. Hogg J. C., Agarawal J. B., Gardiner A. J., Palmer W. H., Macklem P. T. Distribution of airway resistance with developing pulmonary edema in dogs. J Appl Physiol. 1972 Jan;32(1):20–24. doi: 10.1152/jappl.1972.32.1.20. [DOI] [PubMed] [Google Scholar]
  12. KORY R. C., CALLAHAN R., BOREN H. G., SYNER J. C. The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men. Am J Med. 1961 Feb;30:243–258. doi: 10.1016/0002-9343(61)90096-1. [DOI] [PubMed] [Google Scholar]
  13. Lieppe W., Scallion R., Behar V. S., Kisslo J. A. Two-dimensional echocardiographic findings in atrial septal defect. Circulation. 1977 Sep;56(3):447–456. doi: 10.1161/01.cir.56.3.447. [DOI] [PubMed] [Google Scholar]
  14. MCCREDIE R. M., LOVEJOY F. W., Jr, YU P. N. PULMONARY DIFFUSING CAPACITY AND PULMONARY CAPILLARY BLOOD VOLUME IN PATIENTS WITH INTRACARDIAC SHUNTS. J Lab Clin Med. 1964 Jun;63:914–923. [PubMed] [Google Scholar]
  15. Maltz D. L., Treves S. Quantitative radionuclide angiocardiography: determination of Qp: Qs in children. Circulation. 1973 May;47(5):1049–1056. doi: 10.1161/01.cir.47.5.1049. [DOI] [PubMed] [Google Scholar]
  16. POLIS O., SLUYTS R. CORRELATIONS HEMODYNAMIQUES D'UNE DEFORMATION THORACIQUE OBSERVEE DANS LES CARDIOPATHIES CONGENITALES: "LE THORAX DE DAVIES". Acta Cardiol. 1963;18:412–437. [PubMed] [Google Scholar]
  17. ROTMAN H. H., WOOLF C. R. The diffusing capacity of the lungs at rest and on exercise in adults with atrial or ventricular septal defect. Dis Chest. 1963 Jun;43:613–619. doi: 10.1378/chest.43.6.613. [DOI] [PubMed] [Google Scholar]
  18. Troyer A. D., Yernault J. C., Englert M. Mechanics of breathing in patients with atrial septal defect. Am Rev Respir Dis. 1977 Mar;115(3):413–421. doi: 10.1164/arrd.1977.115.3.413. [DOI] [PubMed] [Google Scholar]
  19. Wilhelmsen L., Varnauskas E. Effects of acute plasma expansion on the mechanics of breathing. Clin Sci. 1967 Aug;33(1):29–38. [PubMed] [Google Scholar]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group

RESOURCES