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. 1979 Aug;42(2):214–220. doi: 10.1136/hrt.42.2.214

Plasma adrenaline and noradrenaline concentrations and dopamine-beta-hydroxylase activity in myocardial infarction with and without cardiogenic shock.

C R Benedict, D G Grahame-Smith
PMCID: PMC482137  PMID: 486283

Abstract

In patients with myocardial infarction, with or without cardiogenic shock, plasma noradrenaline and adrenaline concentrations are increased. However, plasma noradrenaline concentrations are considerably higher in patients with cardiogenic shock when compared with those with uncomplicated myocardial infarction. Plasma noradrenaline and adrenaline concentrations showed a sustained increase until death in patients with cardiogenic shock whereas those concentrations were back to normal levels by the end of the third day in patients with uncomplicated myocardial infarction. Plasma dopamine-beta-hydroxylase activities in both the groups were within normal range and did not show any significant variation throughout the period of study.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Axelrod J. Dopamine- -hydroxylase: regulation of its synthesis and release from nerve terminals. Pharmacol Rev. 1972 Jun;24(2):233–243. [PubMed] [Google Scholar]
  2. Brecht H. M., Banthien F., Schoeppe W. Decrease in plasma noradrenaline levels following long-term treatment with prindolol in patients with essential hypertension. Klin Wochenschr. 1976 Nov 15;54(22):1095–1105. doi: 10.1007/BF01469113. [DOI] [PubMed] [Google Scholar]
  3. GAZES P. C., RICHARDSON J. A., WOODS E. F. Plasma catechol amine concentrations in myocardial infarction and angina pectoris. Circulation. 1959 May;19(5):657–661. doi: 10.1161/01.cir.19.5.657. [DOI] [PubMed] [Google Scholar]
  4. Griffiths J., Leung F. The sequential estimation of plasma catecholamines and whole blood histamine in myocardial infarction. Am Heart J. 1971 Aug;82(2):171–179. doi: 10.1016/0002-8703(71)90262-6. [DOI] [PubMed] [Google Scholar]
  5. Gutteberg T., Borud O., Stromme J. H. Dopamine-beta-hydroxylase activity in serum following acute myocardial infarction: an evaluation of this parameter for routine use as an index of sympathetic activity. Clin Chim Acta. 1976 May 17;69(1):61–66. doi: 10.1016/0009-8981(76)90471-x. [DOI] [PubMed] [Google Scholar]
  6. Hayashi K. D., Moss A. J., Yu P. N. Urinary catecholamine excretion in myocardial infarction. Circulation. 1969 Oct;40(4):473–481. doi: 10.1161/01.cir.40.4.473. [DOI] [PubMed] [Google Scholar]
  7. Hörtnagl H., Benedict C. R., Grahame-Smith D. G. A sensitive radioenzymatic assay for adrenaline and noradrenaline in plasma. Br J Clin Pharmacol. 1977 Oct;4(5):553–558. doi: 10.1111/j.1365-2125.1977.tb00785.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Januszewicz W., Sznajderman M., Ciswicka-Sznajderman M., Wocial B., Rymaszewski Z. Plasma free fatty acid and catecholamine levels in patients with acute myocardial infarction. Br Heart J. 1971 Sep;33(5):716–718. doi: 10.1136/hrt.33.5.716. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jewitt D. E., Reid D., Thomas M., Mercer C. J., Valori C., Shillingford J. P. Free noradrenaline and adrenaline excretion in relation to the development of cardiac arrhythmias and heart-failure in patients with acute myocardial infarction. Lancet. 1969 Mar 29;1(7596):635–641. doi: 10.1016/s0140-6736(69)92009-1. [DOI] [PubMed] [Google Scholar]
  10. Killen D. A., Tinsley E. A. Serum enzymes in experimental myocardial infarcts. Relation of blood levels of serum glutamic oxaloacetic transaminase, lactic dehydrogenase, and heat stable lactic dehydrogenase to size of experimental myocardial infarct. Arch Surg. 1966 Mar;92(3):418–422. doi: 10.1001/archsurg.1966.01320210098021. [DOI] [PubMed] [Google Scholar]
  11. Klein R. F., Troyer W. G., Thompson H. K., Bogdonoff M. D., Wallace A. G. Catecholamine excretion in myocardial infarction. Arch Intern Med. 1968 Dec;122(6):476–482. [PubMed] [Google Scholar]
  12. Lukomsky P. E., Oganov R. G. Blood plasma catecholamines and their urinary excretion in patients with acute myocardial infarction. Am Heart J. 1972 Feb;83(2):182–188. doi: 10.1016/0002-8703(72)90137-8. [DOI] [PubMed] [Google Scholar]
  13. McDonald L., Baker C., Bray C., McDonald A., Restieaux N. Plasma-catecholamines after cardiac infarction. Lancet. 1969 Nov 15;2(7629):1021–1023. doi: 10.1016/s0140-6736(69)90637-0. [DOI] [PubMed] [Google Scholar]
  14. Nagatsu T., Udenfriend S. Photometric assay of dopamine- -hydroxylase activity in human blood. Clin Chem. 1972 Sep;18(9):980–983. [PubMed] [Google Scholar]
  15. Prakash R., Parmley W. W., Horvat M., Swan H. J. Serum cortisol, plasma free fatty acids, and urinary cathecholamines as indicators of complications in acute myocardial infarction. Circulation. 1972 Apr;45(4):736–745. doi: 10.1161/01.cir.45.4.736. [DOI] [PubMed] [Google Scholar]
  16. Siggers D. C., Salter C., Fluck D. C. Serial plasma adrenaline and noradrenaline levels in myocardial infarction using a new double isotope technique. Br Heart J. 1971 Nov;33(6):878–883. doi: 10.1136/hrt.33.6.878. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. VON EULERU QUANTITATION OF STRESS BY CATECHOLAMINE ANALYSIS. Clin Pharmacol Ther. 1964 Jul-Aug;5:398–404. doi: 10.1002/cpt196454398. [DOI] [PubMed] [Google Scholar]
  18. Videbaek J., Christensen N. J., Sterndorff B. Serial determination of plasma catecholamines in myocardial infarction. Circulation. 1972 Nov;46(5):846–855. doi: 10.1161/01.cir.46.5.846. [DOI] [PubMed] [Google Scholar]

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