Abstract
The frequency of pericardial disease in scleroderma found at necropsy in high. The clinical recognition of pericarditis with or without effusion is rare and tamponade with haemodynamic impairment is exceptional. Three patients with scleroderma presented with an acute syndrome of dyspnoea, chest pain, and cardiomegaly requiring pericardiocentesis for relief of pericardial tamponade. One patient died. The mechanism of the pericardial effusion remains unknown. The haemodynamic data recorded from one patient suggested that pericardial fibrosis in scleroderma may predispose to pericardial tamponade.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bulkley B. H., Ridolfi R. L., Salyer W. R., Hutchins G. M. Myocardial lesions of progressive systemic sclerosis. A cause of cardiac dysfunction. Circulation. 1976 Mar;53(3):483–490. doi: 10.1161/01.cir.53.3.483. [DOI] [PubMed] [Google Scholar]
- D'Angelo W. A., Fries J. F., Masi A. T., Shulman L. E. Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls. Am J Med. 1969 Mar;46(3):428–440. doi: 10.1016/0002-9343(69)90044-8. [DOI] [PubMed] [Google Scholar]
- McWhorter J. E., 4th, LeRoy E. C. Pericardial disease in scleroderma (systemic sclerosis). Am J Med. 1974 Oct;57(4):566–575. doi: 10.1016/0002-9343(74)90008-4. [DOI] [PubMed] [Google Scholar]
- Medsger T. A., Jr, Masi A. T., Rodnan G. P., Benedek T. G., Robinson H. Survival with systemic sclerosis (scleroderma). A life-table analysis of clinical and demographic factors in 309 patients. Ann Intern Med. 1971 Sep;75(3):369–376. doi: 10.7326/0003-4819-75-3-369. [DOI] [PubMed] [Google Scholar]
- Shabetai R., Fowler N. O., Guntheroth W. G. The hemodynamics of cardiac tamponade and constrictive pericarditis. Am J Cardiol. 1970 Nov;26(5):480–489. doi: 10.1016/0002-9149(70)90706-x. [DOI] [PubMed] [Google Scholar]