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British Heart Journal logoLink to British Heart Journal
. 1979 Oct;42(4):438–441. doi: 10.1136/hrt.42.4.438

Effect of ventricular function on left ventricular ejection time in aortic stenosis.

P Kligfield, P Okin
PMCID: PMC482179  PMID: 508475

Abstract

Since recognition of factors which modify the duration of ejection in aortic stenosis is of clinical importance, the relations among rate-corrected left ventricular ejection time, aortic valve area, and determinants of ventricular performance were studied in 54 catheterised patients. In patients with a normal cardiac index, increasing duration of ejection was linearly related to increasing obstruction. In patients with failing ventricles, on the other hand, the ejection time was less prolonged, and the duration of ejection was unrelated to valve area. At fixed valve area, relation with cardiac output, stroke volume, heart rate, mean aortic valve pressure gradient, mean aortic pressure, and left ventricular end-diastolic pressure could not adequately explain the observed scatter in ejection time. This suggests a multifactorial basis for the wide range of ejection times observed with severe aortic stenosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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