Abstract
Myocardial scintigraphy with 201Tl was performed at rest in a selected group of 36 patients with unequivocal clinical and electrocardiographic evidence of old myocardial infarction. The scintigraphic findings were correlated with electrocardiographic pattern, and with regional left ventricular wall motion and the severity of coronary artery disease defined by contrast angiography. Detection was dependent on the extent of the infarct but was independent of QRS morphology and of the severity of coronary disease. When positive, 201Tl scintigraphy was often a more precise method than the electrocardiogram for localising and delineating the extent of the infarct. Furthermore, the perfusion defect corresponded in location and extent to abnormalities of left ventricular wall motion. The site or severity of coronary artery disease could not be determined from the 201Tl scintigram.
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- Bailey I. K., Griffith L. S., Rouleau J., Strauss W., Pitt B. Thallium-201 myocardial perfusion imaging at rest and during exercise. Comparative sensitivity to electrocardiography in coronary artery disease. Circulation. 1977 Jan;55(1):79–87. doi: 10.1161/01.cir.55.1.79. [DOI] [PubMed] [Google Scholar]
- Baroldi G. Coronary stenosis: ischemic or non-ischemic factor? Am Heart J. 1978 Aug;96(2):139–143. doi: 10.1016/0002-8703(78)90076-5. [DOI] [PubMed] [Google Scholar]
- Baroldi G., Radice F., Schmid G., Leone A. Morphology of acute myocardial infarction in relation to coronary thrombosis. Am Heart J. 1974 Jan;87(1):65–75. doi: 10.1016/0002-8703(74)90392-5. [DOI] [PubMed] [Google Scholar]
- Blood D. K., McCarthy D. M., Sciacca R. R., Cannon P. J. Comparison of single-dose and double-dose thallium-201 myocardial perfusion scintigraphy for the detection of coronary artery disease and prior myocardial infarction. Circulation. 1978 Nov;58(5):777–788. doi: 10.1161/01.cir.58.5.777. [DOI] [PubMed] [Google Scholar]
- Bodenheimer M. M., Banka V. S., Fooshee C., Hermann G. A., Helfant R. H. Relationship between regional myocardial perfusion and the presence, severity and reversibility of asynergy in patients with coronary heart disease. Circulation. 1978 Nov;58(5):789–795. doi: 10.1161/01.cir.58.5.789. [DOI] [PubMed] [Google Scholar]
- Bodenheimer M. M., Banka V. S., Hermann G. A., Trout R. G., Pasdar H., Helfant R. H. Reversible asynergy. Histopathologic and electrographic correlations in patients with coronary artery disease. Circulation. 1976 May;53(5):792–796. doi: 10.1161/01.cir.53.5.792. [DOI] [PubMed] [Google Scholar]
- Botvinick E. H., Taradash M. R., Shames D. M., Parmley W. W. Thallium-20 1 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal and equivocal electrocardiographic stress tests. Am J Cardiol. 1978 Jan;41(1):43–51. doi: 10.1016/0002-9149(78)90130-3. [DOI] [PubMed] [Google Scholar]
- Cohen M. V. The functional value of coronary collaterals in myocardial ischemia and therapeutic approach to enhance collateral flow. Am Heart J. 1978 Mar;95(3):396–404. doi: 10.1016/0002-8703(78)90372-1. [DOI] [PubMed] [Google Scholar]
- Eliot R. S., Baroldi G., Leone A. Necropsy studies in myocardial infarction with minimal or no coronary luminal reduction due to atherosclerosis. Circulation. 1974 Jun;49(6):1127–1131. doi: 10.1161/01.cir.49.6.1127. [DOI] [PubMed] [Google Scholar]
- Helfant R. H., Vokonas P. S., Gorlin R. Functional importance of the human coronary collateral circulation. N Engl J Med. 1971 Jun 10;284(23):1277–1281. doi: 10.1056/NEJM197106102842301. [DOI] [PubMed] [Google Scholar]
- Maseri A., L'Abbate A., Baroldi G., Chierchia S., Marzilli M., Ballestra A. M., Severi S., Parodi O., Biagini A., Distante A. Coronary vasospasm as a possible cause of myocardial infarction. A conclusion derived from the study of "preinfarction" angina. N Engl J Med. 1978 Dec 7;299(23):1271–1277. doi: 10.1056/NEJM197812072992303. [DOI] [PubMed] [Google Scholar]
- McLaughlin P. R., Martin R. P., Doherty P., Daspit S., Goris M., Haskell W., Lewis S., Kriss J. P., Harrison D. C. Reproducibility of thallium-201 myocardial imaging. Circulation. 1977 Mar;55(3):497–503. doi: 10.1161/01.cir.55.3.497. [DOI] [PubMed] [Google Scholar]
- Mueller T. M., Marcus M. L., Ehrhardt J. C., Chaudhuri T., Abboud F. M. Limitations of thallium-201 myocardial perfusion scintigrams. Circulation. 1976 Oct;54(4):640–646. doi: 10.1161/01.cir.54.4.640. [DOI] [PubMed] [Google Scholar]
- Pohost G. M., Zir L. M., Moore R. H., McKusick K. A., Guiney T. E., Beller G. A. Differentiation of transiently ischemic from infarcted myocardium by serial imaging after a single dose of thallium-201. Circulation. 1977 Feb;55(2):294–302. doi: 10.1161/01.cir.55.2.294. [DOI] [PubMed] [Google Scholar]
- Ritchie J. L., Zaret B. L., Strauss H. W., Pitt B., Berman D. S., Schelbert H. R., Ashburn W. L., Berger H. J., Hamilton G. W. Myocardial imaging with thallium-201: a multicenter study in patients with angina pectoris or acute myocardial infarction. Am J Cardiol. 1978 Sep;42(3):345–350. doi: 10.1016/0002-9149(78)90926-8. [DOI] [PubMed] [Google Scholar]
- Wackers F. J., Schoot J. B., Sokole E. B., Samson G., Niftrik G. J., Lie K. I., Durrer D., Wellens H. J. Noninvasive visualization of acute myocardial infarction in man with thallium-201. Br Heart J. 1975 Jul;37(7):741–744. doi: 10.1136/hrt.37.7.741. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wackers F. J., Sokole E. B., Samson G., Schoot J. B., Lie K. I., Liem K. L., Wellens H. J. Value and limitations of thallium-201 scintigraphy in the acute phase of myocardial infarction. N Engl J Med. 1976 Jul 1;295(1):1–5. doi: 10.1056/NEJM197607012950101. [DOI] [PubMed] [Google Scholar]
- Williams R. A., Cohn P. F., Vokonas P. S., Young E., Herman M. V., Gorlin R. Electrocardiographic, arteriographic and ventriculographic correlations in transmural myocardial infarction. Am J Cardiol. 1973 May;31(5):595–599. doi: 10.1016/0002-9149(73)90328-7. [DOI] [PubMed] [Google Scholar]



