Table 4.

Plasma amino acid levels (μmol/L) in stroke placebo and treated subgroups at both admission and discharge.

Amino acid	Placebo (n = 30)		EAAs (n = 30)		Trend over time (interaction; p level)
	Admission	Discharge	Admission	Discharge (p)
Aspartate	20.5 ± 8.2	14.3 ± 5.9	24.5 ± 16.7	11.1 ± 7.8	=0.6
Glutamate	177 ± 100	129.6 ± 19.6	143 ± 116	127.6 ± 45	=0.8
Asparagine	21.5 ± 10.6	20.5 ± 11.9	16.7 ± 6.6	17.7 ± 10.5	=0.5
Serine	72 ± 43	51.4 ± 20	64.5 ± 24	50.2 ± 10.3	=0.9
Glutamine	97 ± 33	124.3 ± 21	104.2 ± 31	128.4 ± 33	=0.7
Histidine	74.2 ± 33	72.6 ± 17	58.2 ± 40.1	64.0 ± 31.3	=0.8
Glycine	157 ± 125	121 ± 24.4	118 ± 60	130 ± 22.5	=0.001
Threonine	223 ± 96	177 ± 61.7	151.3 ± 110	170.3 ± 64	=0.1
Citrulline	20.5 ± 9.9	23.1 ± 10	19 ± 9.5	21.5 ± 9.4	=0.6
3-Methylhistidine	5.5 ± 2.9	8.3 ± 6.2	3.78 ± 1.22	4.5 ± 1.9	=0.7
Alanine	356 ± 195	312 ± 65	216 ± 119	284 ± 112	=0.02
Arginine	136 ± 67.7	200 ± 117	144.2 ± 51	119 ± 45	=0.03
Tyrosine	55.3 ± 27	49.3 ± 16.4	43.7 ± 14.9	48.0 ± 17	=0.05
Cysteine	55.1 ± 29.6	55.2 ± 19	34.4 ± 22.3	45.1 ± 14.5	=0.05
Valine	219 ± 71	214.5 ± 59	180.4 ± 77	193.1 ± 80	=0.8
Methionine	28.6 ± 16	19.7 ± 10.4	17.6 ± 14.4	16.5 ± 9.5	=0.6
Tryptophan	76.4 ± 28	62 ± 14.6	59 ± 40.4	56 ± 41.5	=0.8
Phenylalanine	54.4 ± 21	53.3 ± 16.6	45 ± 17	47.6 ± 24	=0.9
Isoleucine	66.5 ± 23	66.3 ± 20	62.1 ± 33	55.2 ± 21.8	=0.8
Leucine	113 ± 46	108 ± 36	98.1 ± 56	95.2 ± 36	=0.9
Lysine	109 ± 52	97 ± 26.6	95.1 ± 51	94.4 ± 15.5	=0.8
Total AAs	2137 ± 1004	1979 ± 603	1699 ± 913	1833 ± 658.5	=0.02
Total EAAs	890 ± 353	798 ± 247	709 ± 400	728 ± 293	=0.05

EAAs = essential amino acids.

Data are reported as mean ± standard deviation.

Statistical analysis: repeated measures analysis of variance.

Trend over time: interaction differences in trends between groups.