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. 1980 Sep;44(3):352–356. doi: 10.1136/hrt.44.3.352

Primary pulmonary hypertension: effects of nifedipine.

F Camerini, E Alberti, S Klugmann, A Salvi
PMCID: PMC482410  PMID: 7426194

Abstract

The results of the medical treatment of primary pulmonary hypertension are usually very poor. A case of severe primary pulmonary hypertension in chronic heart failure was treated with the calcium antagonist nifedipine, a powerful vasodilator which acts directly on vascular smooth muscle. Nifedipine, administered in a dose of 20 mg sublingually, caused a pronounced fall in pulmonary and systemic vascular resistances (54 and 49%, respectively) and a rise in cardiac output (90.3%). Improvement was maintained over a three-month period. These data suggest that nifedipine can be used in the treatment of this condition.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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