Abstract
The amount of fibrosis in endomyocardial biopsies from 55 patients with aortic stenosis and 42 patients with aortic regurgitaion was measured. Sixty per cent of the patients with aortic stenosis had some degree of fibrosis; the degree of fibrosis correlated strongly with ejection fraction, peak systolic gradient, symptoms of cardiac failure, and mortality. In patients with aortic regurgitation, fibrosis was found in 40 per cent and was never severe. A correlation was found with symptoms of cardiac failure and mortality at follow-up, but not with ejection fraction or degree of regurgitation.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brooksby I. A., Jenkins B. S., Coltart D. J., Webb-Peploe M. M., Davies M. J. Left-ventricular endomyocardial biopsy. Lancet. 1974 Nov 23;2(7891):1222–1225. doi: 10.1016/s0140-6736(74)90744-2. [DOI] [PubMed] [Google Scholar]
- Brooksby I. A., Swanton R. H., Jenkins B. S., Webb-Peploe M. M. Long sheath technique for introduction of catheter tip manometer or endomyocardial bioptome into left or right heart. Br Heart J. 1974 Sep;36(9):908–912. doi: 10.1136/hrt.36.9.908. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kuhn H., Breithardt G., Knieriem H. J., Köhler E., Lösse B., Seipel L., Loogen F. Prognosis and possible presymptomatic manifestations of congestive cardiomyopathy (COCM). Postgrad Med J. 1978 Jul;54(633):451–461. doi: 10.1136/pgmj.54.633.451. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Olsen E. G. Diagnostic value of the endomyocardial bioptome. Lancet. 1974 Apr;1(7859):658–660. doi: 10.1016/s0140-6736(74)93203-6. [DOI] [PubMed] [Google Scholar]
- Richardson P. J. King's endomyocardial bioptome. Lancet. 1974 Apr;1(7859):660–661. doi: 10.1016/s0140-6736(74)93204-8. [DOI] [PubMed] [Google Scholar]