Table 4.
Challenge Groups | Nasal swabsx | BALFx | ||||
---|---|---|---|---|---|---|
| ||||||
1 dpi | 2 dpi | 3 dpi | 4 dpi | 5 dpi | 5 dpi | |
No MDA/NC | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a | 0.0 ± 0.0a |
Homologous | ||||||
No MDA/H1N2 | 1.5 ± 0.4b | 1.9 ± 0.4b | 2.3 ± 0.4b | 2.8 ± 0.3b | 2.8 ± 0.2b | 3.9 ± 0.5b |
WIV-MDA/H1N2 | 0.0 ± 0.0a | 0.1 ± 0.1a | 0.8 ± 0.4a | 0.8 ± 0.4a | 0.1 ± 0.1a | 2.7 ± 0.7b |
Heterologous | ||||||
No MDA/H1N1 | 1.2 ± 0.2b | 1.0 ± 0.1b | 1.0 ± 01a,b | 1.5 ± 0.2b | 1.0 ± 0.2b | 0.7 ± 0.4a |
WIV-MDA/H1N1 | 1.3 ± 0.3b | 0.5 ± 02a,b | 1.4 ± 0.2b | 1.2 ± 0.2b | 1.0 ± 0.2b | 1.3 ± 0.4a |
Virus titers represented as log10 TCID50/ml.
Statistically significant differences in the same column identified with different lowercase letters (P ≤ 0.05).