Table 2. Univariate and multivariable analyses of prognostic factors in lung adenocarcinoma for 5-year survival.
Variable | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
HR | P value | 95% CI | HR | P value | 95% CI | |
MAGE-A9 expression | ||||||
High vs low | 4.728 | 0.001* | 2.989−7.477 | 3.356 | 0.001* | 2.093−5.380 |
Gender | ||||||
Male vs female | 0.510 | 0.002* | 0.330−0.788 | 0.533 | 0.007* | 0.337−0.845 |
Age (years) | ||||||
≤ 60 vs > 60 | 1.308 | 0.220 | 0.851−2.010 | |||
Tumor size (cm) | ||||||
≤ 3 vs > 3 | 2.575 | 0.001* | 1.669−3.972 | 1.616 | 0.066 | 0.968−2.700 |
Differentiation | ||||||
Well and mod vs poorly |
3.422 | 0.001* | 2.247−5.211 | 2.780 | 0.001* | 1.741−4.439 |
Lymph node metastasis | ||||||
Yes vs no | 1.964 | 0.002* | 1.274−3.027 | 1.757 | 0.037* | 1.035−2.983 |
TNM classification | ||||||
stage I vs stage II vs stage III/IV |
1.461 | 0.001* | 1.163−1.835 | 0.907 | 0.590 | 0.636−1.293 |
P < 0.05; CI, confidence interval; HR, hazard ratio.