Figure 4.

Increased frequency of moderate proteinuria in aged PR^−/− mice. Shown are frequencies of moderate proteinuria-free survival in female (A) and male (B) Nba2 mice between 2 and 10 mo. age. Depending on the animal, observation began at either 2 or 4 mo. P values determined by log-rank test. (C) Estimated cumulative proteinuria between 4 and 10 mo. as determine by AUC (see text). Shown are medians (lines) and individual values (symbols). *, p < 0.05 Mann-Whitney test.