Abstract
Nine patients with eosinophilic endomyocardial disease who had undergone angiocardiography with histological staging of their disease, were studied by M-mode and two dimensional echocardiography to determine the extent to which specific features of the disease could be evaluated by these non-invasive methods. In seven patients, amplitude processed two dimensional echocardiography showed regions where the relative intensity of endomyocardial echoes was greater than normal, and their distribution corresponded to known areas of fibrosis. Standard two dimensional echocardiography was normal in all but three patients. In eight patients M-mode echocardiography showed only non-specific abnormalities, but appeared to be useful in assessing the functional consequences of myocardial or mitral valve disease. After digitisation a reduction in the duration and an increase in the peak rate of dimension increase during filling was prolonged. It was concluded that amplitude processed two dimensional echocardiography might be useful in diagnosing the extent and severity of endomyocardial disease in patients with hyperosinophilia. These noninvasive techniques may thus provide a means for the early diagnosis of endomyocardial fibrosis and could be useful in assessing in progression or response to treatment.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chew C. Y., Ziady G. M., Raphael M. J., Nellen M., Oakley C. M. Primary restrictive cardiomyopathy. Non-tropical endomyocardial fibrosis and hypereosinophilic heart disease. Br Heart J. 1977 Apr;39(4):399–413. doi: 10.1136/hrt.39.4.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chivers R. C. Tissue characterization. Ultrasound Med Biol. 1981;7(1):1–20. doi: 10.1016/0301-5629(81)90018-1. [DOI] [PubMed] [Google Scholar]
- Dienot B., Ekra A., Bertrand E. L'échocardiographie dans 23 cas de fibroses endomyocardiques constrictives droites ou bilatérales. Arch Mal Coeur Vaiss. 1979 Oct;72(10):1101–1107. [PubMed] [Google Scholar]
- Gibson D. G., Brown D. Measurement of instantaneous left ventricular dimension and filling rate in man, using echocardiography. Br Heart J. 1973 Nov;35(11):1141–1149. doi: 10.1136/hrt.35.11.1141. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Haertel J. C., Castro I. Avaliaço ecocardiográfica da fibrose endomiocárdica. Arq Bras Cardiol. 1980 Dec;35(6):475–480. [PubMed] [Google Scholar]
- Hess O. M., Turina M., Senning A., Goebel N. H., Scholer Y., Krayenbuehl H. P. Pre- and postoperative findings in patients with endomyocardial fibrosis. Br Heart J. 1978 Apr;40(4):406–415. doi: 10.1136/hrt.40.4.406. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Logan-Sinclair R., Wong C. M., Gibson D. G. Clinical application of amplitude processing of echocardiographic images. Br Heart J. 1981 Jun;45(6):621–627. doi: 10.1136/hrt.45.6.621. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Parrillo J. E., Borer J. S., Henry W. L., Wolff S. M., Fauci A. S. The cardiovascular manifestations of the hypereosinophilic syndrome. Prospective study of 26 patients, with review of the literature. Am J Med. 1979 Oct;67(4):572–582. doi: 10.1016/0002-9343(79)90227-4. [DOI] [PubMed] [Google Scholar]
- Pernod J., Gerbaux A., Vervin P., Terdjman M., Lelguen C., Droniou J. Apport de l'échocardiographie dans le diagnostic des fibroses endomyocardiques. Arch Mal Coeur Vaiss. 1980 Feb;73(2):139–146. [PubMed] [Google Scholar]
- Upton M. T., Gibson D. G. The study of left ventricular function from digitized echocardiograms. Prog Cardiovasc Dis. 1978 Mar-Apr;20(5):359–384. doi: 10.1016/0033-0620(78)90003-8. [DOI] [PubMed] [Google Scholar]
- Weyman A. E., Rankin R., King H. Loeffler's endocarditis presenting as mitral and tricuspid stenosis. Am J Cardiol. 1977 Sep;40(3):438–444. doi: 10.1016/0002-9149(77)90168-0. [DOI] [PubMed] [Google Scholar]