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. 1980 Jun;43(6):648–660. doi: 10.1136/hrt.43.6.648

Pathogenetic mechanisms of angina pectoris: expanding views.

A Maseri
PMCID: PMC482765  PMID: 7426144

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALLISON R. B., RODRIGUEZ F. L., HIGGINS E. A., Jr, LEDDY J. P., ABELMANN W. H., ELLIS L. B., ROBBINS S. L. CLINICOPATHOLOGIC CORRELATIONS IN CORONARY ATHEROSCLEROSIS. FOUR HUNDRED THIRTY PATIENTS STUDIED WITH POSTMORTEM CORONARY ANGIOGRAPHY. Circulation. 1963 Feb;27:170–184. doi: 10.1161/01.cir.27.2.170. [DOI] [PubMed] [Google Scholar]
  2. Berman N. D., McLaughlin P. R., Huckell V. F., Mahon W. A., Morch J. E., Adelman A. G. Prinzmetal's angina with coronary artery spasm. Angiographic, pharmacologic, metabolic and radionuclide perfusion studies. Am J Med. 1976 May 10;60(5):727–732. doi: 10.1016/0002-9343(76)90511-8. [DOI] [PubMed] [Google Scholar]
  3. Berndt T. B., Fitzgerald J., Harrison D. C., Schroeder J. S. Hemodynamic changes at the onset of spontaneous versus pacing-induced angina. Am J Cardiol. 1977 May 26;39(6):784–788. doi: 10.1016/s0002-9149(77)80027-1. [DOI] [PubMed] [Google Scholar]
  4. Bertolasi C. A., Trongé J. E., Carreno C. A., Jalon J., Vega M. R. Unstable angina--prospective and randomized study of its evolution, with and without surgery. Am J Cardiol. 1974 Feb;33(2):201–208. doi: 10.1016/0002-9149(74)90275-6. [DOI] [PubMed] [Google Scholar]
  5. Bobba P., Vecchio C., Di Guglielmo L., Salerno J., Casari A., Montemartini C. Exercise-induced RS-T elevation. Electrocardiographic and angiographic observations. Cardiology. 1972;57(3):162–171. doi: 10.1159/000169514. [DOI] [PubMed] [Google Scholar]
  6. Campeau L., Bourassa M. G., Bois M. A., Saltiel J., Lesperance J., Rico O., Delcan J. L., Telleria M. Clinical significance of selective coronary cinearteriography. Can Med Assoc J. 1968 Dec 7;99(22):1063–1068. [PMC free article] [PubMed] [Google Scholar]
  7. Chahine R. A., Raizner A. E., Ishimori T. The clinical significance of exercise-induced ST-segment elevation. Circulation. 1976 Aug;54(2):209–213. doi: 10.1161/01.cir.54.2.209. [DOI] [PubMed] [Google Scholar]
  8. Clark D. A., Quint R. A., Mitchell R. L., Angell W. W. Coronary artery spasm. medical management, surgical denervation, and autotransplantation. J Thorac Cardiovasc Surg. 1977 Mar;73(3):332–339. [PubMed] [Google Scholar]
  9. Curry R. C., Jr, Pepine C. J., Sabom M. B., Feldman R. L., Christie L. G., Conti C. R. Effects of ergonovine in patients with and without coronary artery disease. Circulation. 1977 Nov;56(5):803–809. doi: 10.1161/01.cir.56.5.803. [DOI] [PubMed] [Google Scholar]
  10. Detry J. M., Mengeot P., Rousseau M. F., Cosyns J., Ponlot R., Brasseur L. A. Maximal exercise testing in patients with spontaneous angina pectoris associated with transiet ST segment elevation. Risks and electrocardiographic findings. Br Heart J. 1975 Sep;37(9):897–903. doi: 10.1136/hrt.37.9.897. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Dhurandhar R. W., Watt D. L., Silver M. D., Trimble A. S., Adelman A. G. Prinzmetal's variant form of angina with arteriographic evidence of coronary arterial spasm. Am J Cardiol. 1972 Dec;30(8):902–905. doi: 10.1016/0002-9149(72)90018-5. [DOI] [PubMed] [Google Scholar]
  12. Distante A., Maseri A., Severi S., Biagini A., Chierchia S. Management of vasospastic angina at rest with continuous infusion of isosorbide dinitrate. A double crossover study in a coronary care unit. Am J Cardiol. 1979 Sep;44(3):533–539. doi: 10.1016/0002-9149(79)90408-9. [DOI] [PubMed] [Google Scholar]
  13. ENOS W. F., HOLMES R. H., BEYER J. Coronary disease among United States soldiers killed in action in Korea; preliminary report. J Am Med Assoc. 1953 Jul 18;152(12):1090–1093. doi: 10.1001/jama.1953.03690120006002. [DOI] [PubMed] [Google Scholar]
  14. Endo M., Hirosawa K., Kaneko N., Hase K., Inoue Y. Prinzmetal's variant angina. Coronary arteriogram and left ventriculogram during angina attack induced by methacholine. N Engl J Med. 1976 Jan 29;294(5):252–255. doi: 10.1056/NEJM197601292940505. [DOI] [PubMed] [Google Scholar]
  15. Endo M., Kanda I., Hosoda S., Hayashi H., Hirosawa K., Konno S. Prinzmetal's variant form of angina pectoris. Re-evaluation of mechanisms. Circulation. 1975 Jul;52(1):33–37. doi: 10.1161/01.cir.52.1.33. [DOI] [PubMed] [Google Scholar]
  16. Fortuin N. J., Friesinger G. C. Exercise-induced S-T segment elevation. Clinical, electrocardiographic and arteriographic studies in twelve patients. Am J Med. 1970 Oct;49(4):459–464. doi: 10.1016/s0002-9343(70)80039-0. [DOI] [PubMed] [Google Scholar]
  17. Friesingerg G. C., Smith R. F. Correlation of electrocardiographic studies and arteriographic findings with angina pectoris. Circulation. 1972 Dec;46(6):1173–1184. doi: 10.1161/01.cir.46.6.1173. [DOI] [PubMed] [Google Scholar]
  18. Fuster V., Frye R. L., Connolly D. C., Danielson M. A., Elveback L. R., Kurland L. T. Arteriographic patterns early in the onset of the coronary syndromes. Br Heart J. 1975 Dec;37(12):1250–1255. doi: 10.1136/hrt.37.12.1250. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. GENSINI G. G., DI GIORGI S., MURAD-NETTO S., BLACK A. Arteriographic demonstration of coronary artery spasm and its release after the use of a vasodilator in a case of angina pectoris and in the experimental animal. Angiology. 1962 Dec;13:550–553. doi: 10.1177/000331976201301202. [DOI] [PubMed] [Google Scholar]
  20. Guazzi M., Polese A., Fiorentini C., Magrini F., Bartorelli C. Left ventricular performance and related haemodynamic changes in Prinzmetal's variant angina pectoris. Br Heart J. 1971 Jan;33(1):84–94. doi: 10.1136/hrt.33.1.84. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Guazzi M., Polese A., Fiorentini C., Magrini F., Olivari M. T., Bartorelli C. Left and right heart haemodynamics during spontaneous angina pectoris. Comparison between angina with ST segment depression and angina with ST segment elevation. Br Heart J. 1975 Apr;37(4):401–413. doi: 10.1136/hrt.37.4.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Helfant R. H. Coronary arterial spasm and provocative testing in ischemic heart disease. Am J Cardiol. 1978 Apr;41(4):787–789. doi: 10.1016/0002-9149(78)90833-0. [DOI] [PubMed] [Google Scholar]
  23. Hillis L. D., Braunwald E. Coronary-artery spasm. N Engl J Med. 1978 Sep 28;299(13):695–702. doi: 10.1056/NEJM197809282991305. [DOI] [PubMed] [Google Scholar]
  24. Hultgren H., Calciano A., Platt F., Abrams H. A clinical evaluation of coronary arteriography. Am J Med. 1967 Feb;42(2):228–247. doi: 10.1016/0002-9343(67)90022-8. [DOI] [PubMed] [Google Scholar]
  25. James T. M. Angina without coronary disease (sic). Circulation. 1970 Aug;42(2):189–191. doi: 10.1161/01.cir.42.2.189. [DOI] [PubMed] [Google Scholar]
  26. James T. N. Pathology of small coronary arteries. Am J Cardiol. 1967 Nov;20(5):679–691. doi: 10.1016/0002-9149(67)90012-4. [DOI] [PubMed] [Google Scholar]
  27. Jouve A., Guiran J. B., Viallet H., Gras A., Blanc M., Arnoux M., Rouvier M., Brunel J. C. Les modifications électrocardiographiques au cours des crises d'angor spontané. Arch Mal Coeur Vaiss. 1969 Mar 3;62(3):331–351. [PubMed] [Google Scholar]
  28. LIKOFF W., KASPARIAN H., SEGAL B. L., NOVACK P., LEHMAN J. S. CLINICAL CORRELATION OF CORONARY ARTERIOGRAPHY. Am J Cardiol. 1965 Aug;16:159–164. doi: 10.1016/0002-9149(65)90469-8. [DOI] [PubMed] [Google Scholar]
  29. Lambert P. R., Hess D. S., Bache R. J. Effect of exercise on perfusion of collateral-dependent myocardium in dogs with chronic coronary artery occlusion. J Clin Invest. 1977 Jan;59(1):1–7. doi: 10.1172/JCI108606. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. MacAlpin R. N., Kattus A. A., Alvaro A. B. Angina pectoris at rest with preservation of exercise capacity: Prinzmetal's variant angina. Circulation. 1973 May;47(5):946–958. doi: 10.1161/01.cir.47.5.946. [DOI] [PubMed] [Google Scholar]
  31. Maseri A., L'Abbate A., Baroldi G., Chierchia S., Marzilli M., Ballestra A. M., Severi S., Parodi O., Biagini A., Distante A. Coronary vasospasm as a possible cause of myocardial infarction. A conclusion derived from the study of "preinfarction" angina. N Engl J Med. 1978 Dec 7;299(23):1271–1277. doi: 10.1056/NEJM197812072992303. [DOI] [PubMed] [Google Scholar]
  32. Maseri A., Parodi O., Severi S., Pesola A. Transient transmural reduction of myocardial blood flow demonstrated by thallium-201 scintigraphy, as a cause of variant angina. Circulation. 1976 Aug;54(2):280–288. doi: 10.1161/01.cir.54.2.280. [DOI] [PubMed] [Google Scholar]
  33. Maseri A., Pesola A., Marzilli M., Severi S., Parodi O., L'Abbate A., Ballestra A. M., Maltinti G., De Nes D. M., Biagini A. Coronary vasospasm in angina pectoris. Lancet. 1977 Apr 2;1(8014):713–717. doi: 10.1016/s0140-6736(77)92164-x. [DOI] [PubMed] [Google Scholar]
  34. Maseri A., Severi S., Nes M. D., L'Abbate A., Chierchia S., Marzilli M., Ballestra A. M., Parodi O., Biagini A., Distante A. "Variant" angina: one aspect of a continuous spectrum of vasospastic myocardial ischemia. Pathogenetic mechanisms, estimated incidence and clinical and coronary arteriographic findings in 138 patients. Am J Cardiol. 1978 Dec;42(6):1019–1035. doi: 10.1016/0002-9149(78)90691-4. [DOI] [PubMed] [Google Scholar]
  35. McLaughlin P. R., Doherty P. W., Martin R. P., Goris M. L., Harrison D. C. Myocardial imaging in a patient with reproducible variant angina. Am J Cardiol. 1977 Jan;39(1):126–129. doi: 10.1016/s0002-9149(77)80023-4. [DOI] [PubMed] [Google Scholar]
  36. Meller J., Pichard A., Dack S. Coronary arterial spasm in Prinzmetal's angina: a proved hypothesis. Am J Cardiol. 1976 May;37(6):938–940. doi: 10.1016/0002-9149(76)90124-7. [DOI] [PubMed] [Google Scholar]
  37. Mudge G. H., Jr, Grossman W., Mills R. M., Jr, Lesch M., Braunwald E. Reflex increase in coronary vascular resistance in patients with ischemic heart disease. N Engl J Med. 1976 Dec 9;295(24):1333–1337. doi: 10.1056/NEJM197612092952401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Muller J. E., Gunther S. J. Nifedipine therapy for Prinzmetal's angina. Circulation. 1978 Jan;57(1):137–139. doi: 10.1161/01.cir.57.1.137. [DOI] [PubMed] [Google Scholar]
  39. Neill W. A., Ritzmann L. W., Selden R. The pathophysiologic basis of acute coronary insufficiency. Observations favoring the hypothesis of intermittent reversible coronary obstruction. Am Heart J. 1977 Oct;94(4):439–444. doi: 10.1016/s0002-8703(77)80037-9. [DOI] [PubMed] [Google Scholar]
  40. Oliva P. B., Potts D. E., Pluss R. G. Coronary arterial spasm in Prinzmetal angina. Documentation by coronary arteriography. N Engl J Med. 1973 Apr 12;288(15):745–751. doi: 10.1056/NEJM197304122881501. [DOI] [PubMed] [Google Scholar]
  41. PRINZMETAL M., KENNAMER R., MERLISS R., WADA T., BOR N. Angina pectoris. I. A variant form of angina pectoris; preliminary report. Am J Med. 1959 Sep;27:375–388. doi: 10.1016/0002-9343(59)90003-8. [DOI] [PubMed] [Google Scholar]
  42. Parodi O., Maseri A., Simonetti I. Management of unstable angina at rest by verapamil. A double-blind cross-over study in coronary care unit. Br Heart J. 1979 Feb;41(2):167–174. doi: 10.1136/hrt.41.2.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Proudfit W. L., Shirey E. K., Sheldon W. C., Sones F. M., Jr Certain clinical characteristics correlated with extent of obstructive lesions demonstrated by selective cine-coronary arteriography. Circulation. 1968 Nov;38(5):947–954. doi: 10.1161/01.cir.38.5.947. [DOI] [PubMed] [Google Scholar]
  44. Proudfit W. L., Shirey E. K., Sones F. M., Jr Distribution of arterial lesions demonstrated by selective cinecoronary arteriography. Circulation. 1967 Jul;36(1):54–62. doi: 10.1161/01.cir.36.1.54. [DOI] [PubMed] [Google Scholar]
  45. Redwood D. R., Epstein S. E. Uses and limitations of stress testing in the evaluation of ischemic heart disease. Circulation. 1972 Dec;46(6):1115–1131. doi: 10.1161/01.cir.46.6.1115. [DOI] [PubMed] [Google Scholar]
  46. Ricci D. R., Orlick A. E., Doherty P. W., Cipriano P. R., Harrison D. C. Reduction of coronary blood flow during coronary artery spasm occurring spontaneously and after provocation by ergonovine maleate. Circulation. 1978 Feb;57(2):392–395. doi: 10.1161/01.cir.57.2.392. [DOI] [PubMed] [Google Scholar]
  47. Robinson B. F. Relation of heart rate and systolic blood pressure to the onset of pain in angina pectoris. Circulation. 1967 Jun;35(6):1073–1083. doi: 10.1161/01.cir.35.6.1073. [DOI] [PubMed] [Google Scholar]
  48. Roughgarden J. W., Newman E. V. Circulatory changes during the pain of angina pectoris. 1772-1965--a critical review. Am J Med. 1966 Dec;41(6):935–946. doi: 10.1016/0002-9343(66)90051-9. [DOI] [PubMed] [Google Scholar]
  49. Schang S. J., Jr, Pepine C. J. Transient asymptomatic S-T segment depression during daily activity. Am J Cardiol. 1977 Mar;39(3):396–402. doi: 10.1016/s0002-9149(77)80095-7. [DOI] [PubMed] [Google Scholar]
  50. Specchia G., de Servi S., Falcone C., Bramucci E., Angoli L., Mussini A., Marinoni G. P., Montemartini C., Bobba P. Coronary arterial spasm as a cause of exercise-induced ST-segment elevation in patients with variant angina. Circulation. 1979 May;59(5):948–954. doi: 10.1161/01.cir.59.5.948. [DOI] [PubMed] [Google Scholar]
  51. Vatner S. F., Millard R. W., Patrick T. A., Heyndrickx G. R. Effects of isoproterenol on regional myocardial function, electrogram, and blood flow in conscious dogs with myocardial ischemia. J Clin Invest. 1976 May;57(5):1261–1271. doi: 10.1172/JCI108394. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Wiener L., Kasparian H., Duca P. R., Walinsky P., Gottlieb R. S., Hanckel F., Brest A. N. Spectrum of coronary arterial spasm. Clinical, angiographic and myocardial metabolic experience in 29 cases. Am J Cardiol. 1976 Dec;38(7):945–955. doi: 10.1016/0002-9149(76)90808-0. [DOI] [PubMed] [Google Scholar]
  53. Yasue H., Omote S., Takizawa A., Nagao M., Miwa K., Tanaka S. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. Circulation. 1979 May;59(5):938–948. doi: 10.1161/01.cir.59.5.938. [DOI] [PubMed] [Google Scholar]
  54. Yasue H., Touyama M., Shimamoto M., Kato H., Tanaka S. Role of autonomic nervous system in the pathogenesis of Prinzmetal's variant form of angina. Circulation. 1974 Sep;50(3):534–539. doi: 10.1161/01.cir.50.3.534. [DOI] [PubMed] [Google Scholar]

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