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. 1978 Apr;40(4):393–400. doi: 10.1136/hrt.40.4.393

Coronary artery ectasia--a variant of occlusive coronary arteriosclerosis.

R H Swanton, M L Thomas, D J Coltart, B S Jenkins, M M Webb-Peploe, B T Williams
PMCID: PMC482810  PMID: 646906

Abstract

In a study of 1000 consecutive coronary arteriograms, 12 patients (all men) had coronary artery ectasia. Ectasia was found most frequently in the circumflex or right coronary artery. Only 1 patient had ectasia in the left anterior descending coronary artery. In 11 patients, ectasia of one artery was associated with severe stenosis or occlusion of other vessels, typical of arteriosclerosis. Histology from an ectatic segment in one of this group showed changes of severe arteriosclerosis with extensive intimal fibrosis and destruction of the media. One patient had a mixed collagen vascular disease. Measurement of coronary sinus flow in 2 patients with coronary artery ectasia showed flows in the range of patients with non-ectatic coronary artery disease. At cardiac surgery flows down the graft to ectatic arteries were in the same range as in grafts to non-ectatic vessels. Patients with coronary artery ectasia should be anticoagulated.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ashton N., Munro M. CORONARY ARTERY ANEURYSM WITH OCCLUSION DUE TO A CALCIFIED THROMBUS. Br Heart J. 1948 Jul;10(3):165–166. [PMC free article] [PubMed] [Google Scholar]
  2. BOSCHETTI A. E., LEVINE A. Cystic medionecrosis with dissecting aneurysm of coronary arteries. AMA Arch Intern Med. 1958 Oct;102(4):562–570. doi: 10.1001/archinte.1958.00260210048008. [DOI] [PubMed] [Google Scholar]
  3. Barboriak J. J., Rimm A. A., Anderson A. J., Tristani F. E., Walker J. A., Flemma R. J. Coronary artery occlusion and blood lipids. Am Heart J. 1974 Jun;87(6):716–721. doi: 10.1016/0002-8703(74)90416-5. [DOI] [PubMed] [Google Scholar]
  4. Barrand K. G., Brooksby I. A., Webb-Peploe M. M., Braimbridge M. V. Anomalous origin of left coronary artery from pulmonary artery. Surgical considerations in the adult. Br Heart J. 1975 Apr;37(4):441–444. doi: 10.1136/hrt.37.4.441. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Befeler B., Aranda M. J., Embi A., Mullin F. L., El-Sherif N., Lazzara R. Coronary artery aneurysms: study of the etiology, clinical course and effect on left ventricular function and prognosis. Am J Med. 1977 Apr;62(4):597–607. doi: 10.1016/0002-9343(77)90423-5. [DOI] [PubMed] [Google Scholar]
  6. Bing R. J., Rickart A., Hellberg K. Techniques to measure coronary blood flow in man. Am J Cardiol. 1972 Jan;29(1):75–80. doi: 10.1016/0002-9149(72)90419-5. [DOI] [PubMed] [Google Scholar]
  7. Björk L. Ectasia of the coronary arteries. Radiology. 1966 Jul;87(1):33–34. doi: 10.1148/87.1.33. [DOI] [PubMed] [Google Scholar]
  8. Callum K. G., Gaunt J. I., Thomas M. L., Browse N. L. Physiological studies in arteriomegaly. Cardiovasc Res. 1974 May;8(3):373–383. doi: 10.1093/cvr/8.3.373. [DOI] [PubMed] [Google Scholar]
  9. Chaithiraphan S., Goldberg E., O'Reilly M., Jootar P. Multiple aneurysms of coronary artery in sclerodermal heart disease. Angiology. 1973 Feb;24(2):86–93. doi: 10.1177/000331977302400204. [DOI] [PubMed] [Google Scholar]
  10. Chamberlain J. L., 3rd, Perry L. W. Infantile periarteritis nodosa with coronary and brachial aneurysms: a case diagnosed during life. J Pediatr. 1971 Jun;78(6):1039–1042. doi: 10.1016/s0022-3476(71)80439-0. [DOI] [PubMed] [Google Scholar]
  11. Cohen L. S., Elliott W. C., Klein M. D., Gorlin R. Coronary heart disease. Clinical, cinearteriographic and metabolic correlations. Am J Cardiol. 1966 Feb;17(2):153–168. doi: 10.1016/0002-9149(66)90347-x. [DOI] [PubMed] [Google Scholar]
  12. Crook B. R., Raftery E. B., Oram S. Mycotic aneurysms of coronary arteries. Br Heart J. 1973 Jan;35(1):107–109. doi: 10.1136/hrt.35.1.107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. DAOUD A. S., PANKIN D., TULGAN H., FLORENTIN R. A. Aneurysms of the coronary artery. Report of ten cases and review of literature. Am J Cardiol. 1963 Feb;11:228–237. doi: 10.1016/0002-9149(63)90064-x. [DOI] [PubMed] [Google Scholar]
  14. Ebert P. A., Peter R. H., Gunnells J. C., Sabiston D. C., Jr Resecting and grafting of coronary artery aneurysm. Circulation. 1971 Apr;43(4):593–598. doi: 10.1161/01.cir.43.4.593. [DOI] [PubMed] [Google Scholar]
  15. GORE I., SMITH J., CLANCY R. Congenital aneurysms of the coronary arteries with report of a case. Circulation. 1959 Feb;19(2):221–227. doi: 10.1161/01.cir.19.2.221. [DOI] [PubMed] [Google Scholar]
  16. Ganz W., Tamura K., Marcus H. S., Donoso R., Yoshida S., Swan H. J. Measurement of coronary sinus blood flow by continuous thermodilution in man. Circulation. 1971 Aug;44(2):181–195. doi: 10.1161/01.cir.44.2.181. [DOI] [PubMed] [Google Scholar]
  17. Gooch A. S., Vicencio F., Maranhao V., Goldberg H. Arrhythmias and left ventricular asynergy in the prolapsing mitral leaflet syndrome. Am J Cardiol. 1972 May;29(5):611–620. doi: 10.1016/0002-9149(72)90161-0. [DOI] [PubMed] [Google Scholar]
  18. IGLAUER A., SCHWARZ J., KROOVAND W. H. Dissecting aneurysm of coronary artery producing myomalacia and death. Am Heart J. 1959 Apr;57(4):630–637. doi: 10.1016/0002-8703(59)90038-9. [DOI] [PubMed] [Google Scholar]
  19. Imahori S., Bannerman R. M., Graf C. J., Brennan J. C. Ehlers-Danlos syndrome with multiple arterial lesions. Am J Med. 1969 Dec;47(6):967–977. doi: 10.1016/0002-9343(69)90210-1. [DOI] [PubMed] [Google Scholar]
  20. Kato H., Koike S., Yamamoto M., Ito Y., Yano E. Coronary aneurysms in infants and young children with acute febrile mucocutaneous lymph node syndrome. J Pediatr. 1975 Jun;86(6):892–898. doi: 10.1016/s0022-3476(75)80220-4. [DOI] [PubMed] [Google Scholar]
  21. Konecke L. L., Spitzer S., Mason D., Kasparian H., James P. M., Jr Traumatic aneurysm of the left coronary artery. Am J Cardiol. 1971 Feb;27(2):221–223. doi: 10.1016/0002-9149(71)90262-1. [DOI] [PubMed] [Google Scholar]
  22. Markis J. E., Joffe C. D., Cohn P. F., Feen D. J., Herman M. V., Gorlin R. Clinical significance of coronary arterial ectasia. Am J Cardiol. 1976 Feb;37(2):217–222. doi: 10.1016/0002-9149(76)90315-5. [DOI] [PubMed] [Google Scholar]
  23. McKeown F. DISSECTING ANEURYSM OF THE CORONARY ARTERY IN ARACHNODACTYLY. Br Heart J. 1960 Jun;22(3):434–436. doi: 10.1136/hrt.22.3.434. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. McMartin D. E., Stone A. J., Franch R. H. Multiple coronary-artery aneurysms in a child with angina pectoris. N Engl J Med. 1974 Mar 21;290(12):669–670. doi: 10.1056/NEJM197403212901208. [DOI] [PubMed] [Google Scholar]
  25. Murray R. G., Tweddel A., Third J. L., Hutton I., Hillis W. S., Lorimer A. R., Lawrie T. D. Relation between extent of coronary artery disease and severity of hyperlipoproteinaemia. Br Heart J. 1975 Dec;37(12):1205–1209. doi: 10.1136/hrt.37.12.1205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Salel A. F., Riggs K., Mason D. T., Amsterdam E. A., Zelis R. The importance of type IV hyperlipoproteinemia as a predisposing factor in coronary artery disease. Am J Med. 1974 Dec;57(6):897–903. doi: 10.1016/0002-9343(74)90167-3. [DOI] [PubMed] [Google Scholar]
  27. Seabra-Gomes R., Somerville J., Ross D. N., Emanuel R., Parker D. J., Wong M. Congenital coronary artery aneurysms. Br Heart J. 1974 Apr;36(4):329–335. doi: 10.1136/hrt.36.4.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Sherkat A., Kavanagh-Gray D., Edworthy J. Localized aneurysms of the coronary arteries. Radiology. 1967 Jul;89(1):24–26. doi: 10.1148/89.1.24. [DOI] [PubMed] [Google Scholar]
  29. Thomas M. L. Arteriomegaly. Br J Surg. 1971 Sep;58(9):690–694. doi: 10.1002/bjs.1800580915. [DOI] [PubMed] [Google Scholar]
  30. Vieweg W. V., Alpert J. S., Hagan A. D. Caliber and distribution of normal coronary arterial anatomy. Cathet Cardiovasc Diagn. 1976;2(3):269–280. doi: 10.1002/ccd.1810020304. [DOI] [PubMed] [Google Scholar]

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