Abstract
Sixty-nine patients over age 35 with severe valvular aortic stenosis were investigated for concomitant coronary artery disease. Forty (57.9%) had clinical angina pectoris. Sixteen (23.2%) had significant coronary occlusive disease by arteriography. Of those with angina, 13 patients (32.5) had significant coronary arterial obstruction, while in the pain-free group only (10.3%) had occlusive coronary disease. It is concluded that patients with severe aortic stenosis who are free of angina have only a small, but definite, chance of having significant coronary disease.
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Selected References
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- ANDERSON M. W., KELSEY J. R., Jr, EDWARDS J. E. Clinical and pathological considerations in cases of calcific aortic stenosis. J Am Med Assoc. 1952 May 3;149(1):9–15. doi: 10.1001/jama.1952.02930180011003. [DOI] [PubMed] [Google Scholar]
- Coleman E. H., Soloff L. A. Incidence of significant coronary artery disease in rheumatic valvular heart disease. Am J Cardiol. 1970 Apr;25(4):401–404. doi: 10.1016/0002-9149(70)90004-4. [DOI] [PubMed] [Google Scholar]
- Fallen E. L., Elliott W. C., Gorlin R. Mechanisms of angina in aortic stenosis. Circulation. 1967 Oct;36(4):480–488. doi: 10.1161/01.cir.36.4.480. [DOI] [PubMed] [Google Scholar]
- Loew D. E., Harken D. E., Ellis L. B. Valvular heart disease: undiagnosed valvular involvement, concomitant coronary artery disease and systemic embolization. Am J Cardiol. 1972 Aug;30(3):222–228. doi: 10.1016/0002-9149(72)90062-8. [DOI] [PubMed] [Google Scholar]
- Loop F. D., Favaloro R. G., Shirey E. K., Groves L. K., Effler D. B. Surgery for combined valvular and coronary heart disease. JAMA. 1972 Apr 17;220(3):372–376. [PubMed] [Google Scholar]
- Nakib A., Lillehei C. W., Edwards J. E. The degree of coronary atherosclerosis in aortic valvular disease. Arch Pathol. 1965 Nov;80(5):517–520. [PubMed] [Google Scholar]
- Vincent W. R., Buckberg G. D., Hoffman J. I. Left ventricular subendocardial ischemia in severe valvar and supravalvar aortic stenosis. A common mechanism. Circulation. 1974 Feb;49(2):326–333. doi: 10.1161/01.cir.49.2.326. [DOI] [PubMed] [Google Scholar]
