Abstract
This report presents a serious adverse reaction to the anticonvulsant compound carbamazepine. A woman was admitted to hospital for recurrent attacks of syncope. She suffered from atrioventricular block of the Mobitz type II. Carbamazepine suppressed the conduction in her already defective Purkinje fibres and induced ventricular stand-still with subsequent Adams-Stokes attacks.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Caracta A. R., Damato A. N., Josephson M. E., Ricciutti M. A., Gallagher J. J., Lau S. H. Electrophysiologic properties of diphenylhydantoin. Circulation. 1973 Jun;47(6):1234–1241. doi: 10.1161/01.cir.47.6.1234. [DOI] [PubMed] [Google Scholar]
- Steiner C., Wit A. L., Weiss M. B., Damato A. N. The antiarrhythmic actions of carbamazepine (Tegretol). J Pharmacol Exp Ther. 1970 Jun;173(2):323–335. [PubMed] [Google Scholar]