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. 1975 Jun;37(6):668–671. doi: 10.1136/hrt.37.6.668

Advanced heart block aggravated by carbamazepine.

B Beermann, O Edhag, H Vallin
PMCID: PMC482854  PMID: 1148068

Abstract

This report presents a serious adverse reaction to the anticonvulsant compound carbamazepine. A woman was admitted to hospital for recurrent attacks of syncope. She suffered from atrioventricular block of the Mobitz type II. Carbamazepine suppressed the conduction in her already defective Purkinje fibres and induced ventricular stand-still with subsequent Adams-Stokes attacks.

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Selected References

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  1. Caracta A. R., Damato A. N., Josephson M. E., Ricciutti M. A., Gallagher J. J., Lau S. H. Electrophysiologic properties of diphenylhydantoin. Circulation. 1973 Jun;47(6):1234–1241. doi: 10.1161/01.cir.47.6.1234. [DOI] [PubMed] [Google Scholar]
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