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. 1975 Sep;37(9):956–962. doi: 10.1136/hrt.37.9.956

Comparative study of sinoatrial conduction time and sinus node recovery time.

G Steinbeck, B Lüderitz
PMCID: PMC482903  PMID: 1191456

Abstract

Atrial stimulation were performed in 5 normal patients (group A) and 4 patients with electrocardiographic evidence of sinoatrial disease (group B). The technique of premature atrial stimulation was used to calculate sinoatrial conduction time. Rapid atrial pacing was applied to measure maximum sinus node recovery time. In 4 cases both stimulation methods were repeated after intravenous administration of atropine Group A had a sinoatrial conduction time of 56 ms +/- 11 (SD) and a maximum sinus node recovery time of 1122 ms +/- 158. In 3 out of 4 patients with sinus node dysfunction a prolongation of sinoatrial conduction time could be demonstrated (145, 105, and 150 ms). In addition, one showed probable sinus node exit block after premature atrial stimulation. Sinus node recovery time was excessively prolonged in 2 (3880 and 3215 ms) and normal in the other 2 patients with sinoatrial disease (1330 and 1275 ms). Atropine leads to a decrease of sinoatrial conduction time. Results indicate that sinus node recovery time may not be a reliable indicator of sinus node automaticity if sinoatrial conduction is disturbed. The premature atrial stimulation technique makes it possible to study the pattern of sinoatrial conduction and to evaluate its reaction to therapeutic drugs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bashour T., Hemb R., Strauss H. C., Bigger J. T., Jr, Wickramesekaran R. Letter: An unusual effect of atropine on overdrive suppression. Circulation. 1973 Oct;48(4):911–913. doi: 10.1161/01.cir.48.4.911. [DOI] [PubMed] [Google Scholar]
  2. Bashour T., Hemb R., Strauss H. C., Bigger J. T., Jr, Wickramesekaran R. Letter: An unusual effect of atropine on overdrive suppression. Circulation. 1973 Oct;48(4):911–913. doi: 10.1161/01.cir.48.4.911. [DOI] [PubMed] [Google Scholar]
  3. Bonke F. I., Bouman L. N., van Rijn H. E. Change of cardiac rhythm in the rabbit after an atrial premature beat. Circ Res. 1969 Apr;24(4):533–544. doi: 10.1161/01.res.24.4.533. [DOI] [PubMed] [Google Scholar]
  4. Goldreyer B. N., Damato A. N. Sinoatrial-node entrance block. Circulation. 1971 Nov;44(5):789–802. doi: 10.1161/01.cir.44.5.789. [DOI] [PubMed] [Google Scholar]
  5. Gupta P. K., Lichstein E., Chadda K. D., Badui E. Appraisal of sinus nodal recovery time in patients with sick sinus syndrome. Am J Cardiol. 1974 Sep;34(3):265–270. doi: 10.1016/0002-9149(74)90025-3. [DOI] [PubMed] [Google Scholar]
  6. Klein H. O., Singer D. H., Hoffman B. F. Effects of atrial premature systoles on sinus rhythm in the rabbit. Circ Res. 1973 Apr;32(4):480–491. doi: 10.1161/01.res.32.4.480. [DOI] [PubMed] [Google Scholar]
  7. Mandel W. J., Hayakawa H., Allen H. N., Danzig R., Kermaier A. I. Assessment of sinus node function in patients with the sick sinus syndrome. Circulation. 1972 Oct;46(4):761–769. doi: 10.1161/01.cir.46.4.761. [DOI] [PubMed] [Google Scholar]
  8. Mandel W., Hayakawa H., Danzig R., Marcus H. S. Evaluation of sino-atrial node function in man by overdrive suppression. Circulation. 1971 Jul;44(1):59–66. doi: 10.1161/01.cir.44.1.59. [DOI] [PubMed] [Google Scholar]
  9. Miller H. C., Strauss H. C. Measurement of sinoatrial conduction time by premature atrial stimulation in the rabbit. Circ Res. 1974 Dec;35(6):935–947. doi: 10.1161/01.res.35.6.935. [DOI] [PubMed] [Google Scholar]
  10. Narula O. S., Samet P., Javier R. P. Significance of the sinus-node recovery time. Circulation. 1972 Jan;45(1):140–158. doi: 10.1161/01.cir.45.1.140. [DOI] [PubMed] [Google Scholar]
  11. Rosen K. M., Loeb H. S., Sinno M. Z., Rahimtoola S. H., Gunnar R. M. Cardiac conduction in patients with symptomatic sinus node disease. Circulation. 1971 Jun;43(6):836–844. doi: 10.1161/01.cir.43.6.836. [DOI] [PubMed] [Google Scholar]
  12. SANO T., YAMAGISHI S. SPREAD OF EXCITATION FROM THE SINUS NODE. Circ Res. 1965 May;16:423–430. doi: 10.1161/01.res.16.5.423. [DOI] [PubMed] [Google Scholar]
  13. Steinbeck G., Körber H. J., Luberitz B. Die Bestimmung der sinuatrialen Leitungszeit beim Menschen durch gekoppelte atriale Einzelstimulation. Klin Wochenschr. 1974 Dec 15;52(24):1151–1157. doi: 10.1007/BF01466733. [DOI] [PubMed] [Google Scholar]
  14. Strauss H. C., Bigger J. T., Jr Electrophysiological properties of the rabbit sinoatrial perinodal fibers. Circ Res. 1972 Oct;31(4):490–506. doi: 10.1161/01.res.31.4.490. [DOI] [PubMed] [Google Scholar]
  15. Strauss H. C., Saroff A. L., Bigger J. T., Jr, Giardina E. G. Premature atrial stimulation as a key to the understanding of sinoatrial conduction in man. Presentation of data and critical review of the literature. Circulation. 1973 Jan;47(1):86–93. doi: 10.1161/01.cir.47.1.86. [DOI] [PubMed] [Google Scholar]
  16. WEST T. C. Ultramicroelectrode recording from the cardiac pacemaker. J Pharmacol Exp Ther. 1955 Nov;115(3):283–290. [PubMed] [Google Scholar]

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