Abstract
Coronary arteriography in 300 patients within one year of onset of symptoms of coronary arterial disease revealed already severe anatomical coronary disease in three patient groups: those with angina pectoris alone (164 patients), with subendocardial myocardial infarction (63 patients), and with transmural myocardial infarction (73 patients). The number of vessels diseased (larger than or equal to 50% obstruction), distribution of obstruction, and degree of stenosis were similar in the three groups. However, total occlusion of at least one artery was much more common in transmural myocardial infarction and in subendocardial myocardial infarction with elevation of enzyme levels. We suggest that such occlusions occurred at the time of the infarction. Similarities in coronary anatomy between patient subgroups with angina (on exercise or at rest and nocturnal) indicate that factors other than coronary anatomy intervene in precipitating the different types of angina. Vessel disease was not related to smoking, hyperlipidaemia, or hypertension but coronary disease was manifest earlier in life in smokers or those with hyperlipidaemia.
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Selected References
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- Bemis C. E., Gorlin R., Kemp H. G., Herman M. V. Progression of coronary artery disease. A clinical arteriographic study. Circulation. 1973 Mar;47(3):455–464. doi: 10.1161/01.cir.47.3.455. [DOI] [PubMed] [Google Scholar]
- Bruschke A. V., Proudfit W. L., Sones F. M., Jr Progress study of 590 consecutive nonsurgical cases of coronary disease followed 5-9 years. II. Ventriculographic and other correlations. Circulation. 1973 Jun;47(6):1154–1163. doi: 10.1161/01.cir.47.6.1154. [DOI] [PubMed] [Google Scholar]
- Frank C. W., Weinblatt E., Shapiro S. Angina pectoris in men. Prognostic significance of selected medical factors. Circulation. 1973 Mar;47(3):509–517. doi: 10.1161/01.cir.47.3.509. [DOI] [PubMed] [Google Scholar]
- Parker J. O., Di Giorgi S., West R. O. Selective coronary arteriography: arteriographic patterns in coronary heart disease. Can Med Assoc J. 1966 Aug 13;95(7):291–294. [PMC free article] [PubMed] [Google Scholar]
- Proudfit W. L., Shirey E. K., Sheldon W. C., Sones F. M., Jr Certain clinical characteristics correlated with extent of obstructive lesions demonstrated by selective cine-coronary arteriography. Circulation. 1968 Nov;38(5):947–954. doi: 10.1161/01.cir.38.5.947. [DOI] [PubMed] [Google Scholar]
- Roberts W. C. Coronary arteries in fatal acute myocardial infarction. Circulation. 1972 Jan;45(1):215–230. doi: 10.1161/01.cir.45.1.215. [DOI] [PubMed] [Google Scholar]
- SONES F. M., Jr, SHIREY E. K. Cine coronary arteriography. Mod Concepts Cardiovasc Dis. 1962 Jul;31:735–738. [PubMed] [Google Scholar]