Skip to main content
. 2016 Apr 11;4:e1888. doi: 10.7717/peerj.1888

Figure 2. Autophagy was down-regulated after knockdown of IR.

Figure 2

(A) After 200 nM insulin stimulation for 30 min, the expression of LC3ll were decreased in cells transfected with IR shRNA with or without 50 uM chloroquine (CQ), compared with control shRNA. P < 0.05 vs. control shRNA. (B) After 200 nM insulin stimulation for 30 min, the expression of BECLIN1 were decreased, but P62 was up-regulated in cells transfected with IR shRNA, compared with control shRNA. P < 0.05 vs. control shRNA.