. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: Prostate. 2015 Sep 7;75(16):1926–1933. doi: 10.1002/pros.23090

Table II.

Estimates from the Cox model that included clinical factors (left) and the model that included clinical factors and the four markers (right), both fit in the PHS cohort. Age was coded in years, and Gleason score was modeled continuously with a score of 4 + 3 set to 7.5.

	HR (95% CI)	p
Gleason score	3.22 (2.04–5.07)	< 0.001
Age at diagnosis	1.09 (1.03–1.15)	0.004

	HR (95% CI)	p
Gleason score	2.84 (1.70–4.74)	< 0.001
Age at diagnosis	1.09 (1.03–1.16)	0.005
SPP1	1.04 (1.00–1.07)	0.02
PTEN	0.36 (0.02–7.66)	0.51
SMAD4	0.97 (0.94–1.00)	0.04
CCND1	1.00 (0.98–1.03)	0.89