Abstract
The wall thickness of the left ventricle was measured in the hearts of 16 children and 2 adults who died of congenital pulmonary valve stenosis. A right-to-left shunt through a patent foramen ovale had existed in 12 cases and was excluded in the other 6. The thickness of the left ventricular wall and the interventricular septum was increased in the majority of hearts, especially in the older patients. There was a good correlation between wall thickness and histological appearance of the left ventricular myocardium; in 2 cases there was also evidence of left ventricular myocardial fibrosis. The coronary arteries appeared normal in all cases. A direct interaction between the ventricles was thought to be a possible mechanism.
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- Archie J. P., Fixler D. E., Ullyot D. J., Buckberg G. D., Hoffman J. I. Regional myocardial blood flow in lambs with concentric right ventricular hypertrophy. Circ Res. 1974 Feb;34(2):143–154. doi: 10.1161/01.res.34.2.143. [DOI] [PubMed] [Google Scholar]
- BUCHER K., VON CAPELLER D. Mechanismen der gegenseitigen Anpassung von Lungen- und Körperkreislauf. V. Regulationsmechanismen bei einseitiger Minutenvolumenänderung. Helv Physiol Pharmacol Acta. 1954;12(3):253–263. [PubMed] [Google Scholar]
- Bemis C. E., Serur J. R., Borkenhagen D., Sonnenblick E. H., Urschel C. W. Influence of right ventricular filling pressure on left ventricular pressure and dimension. Circ Res. 1974 Apr;34(4):498–504. doi: 10.1161/01.res.34.4.498. [DOI] [PubMed] [Google Scholar]
- Beçu L., Somerville J., Gallo A. 'Isolated' pulmonary valve stenosis as part of more widespread cardiovascular disease. Br Heart J. 1976 May;38(5):472–482. doi: 10.1136/hrt.38.5.472. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elzinga G., van Grondelle R., Westerhof N., van den Bos G. C. Ventricular interference. Am J Physiol. 1974 Apr;226(4):941–947. doi: 10.1152/ajplegacy.1974.226.4.941. [DOI] [PubMed] [Google Scholar]
- LEV M., ROWLATT U. F., RIMOLDI H. J. Pathologic methods for study of congenitally malformed heart. Methods for electrocardiographic and physiologic correlation. Arch Pathol. 1961 Nov;72:493–511. [PubMed] [Google Scholar]
- Laks M. M., Morady F., Garner D., Swan H. J. Relation of ventricular volume, compliance, and mass in the normal and pulmonary arterial banded canine heart. Cardiovasc Res. 1972 Mar;6(2):187–198. doi: 10.1093/cvr/6.2.187. [DOI] [PubMed] [Google Scholar]
- Laks M. M., Morady F., Swan H. J. Canine right and left ventricular cell and sarcomere lengths after banding the pulmonary artery. Circ Res. 1969 May;24(5):705–710. doi: 10.1161/01.res.24.5.705. [DOI] [PubMed] [Google Scholar]
- Moulopoulos S. D., Sarcas A., Stamatelopoulos S., Arealis E. Left ventricular performance during by-pass or distension of the right ventricle. Circ Res. 1965 Dec;17(6):484–491. doi: 10.1161/01.res.17.6.484. [DOI] [PubMed] [Google Scholar]
- Rao B. S., Cohn K. E., Eldridge F. L., Hancock E. W. Left ventricular failure secondary to chronic pulmonary disease. Am J Med. 1968 Aug;45(2):229–241. doi: 10.1016/0002-9343(68)90041-7. [DOI] [PubMed] [Google Scholar]
- Spann J. F., Jr, Buccino R. A., Sonnenblick E. H., Braunwald E. Contractile state of cardiac muscle obtained from cats with experimentally produced ventricular hypertrophy and heart failure. Circ Res. 1967 Sep;21(3):341–354. doi: 10.1161/01.res.21.3.341. [DOI] [PubMed] [Google Scholar]
- ULLRICH K. J., RIECKER G., KRAMER K. Das Druckvolumdiagramm des Warmblüterherzens; isometrische Gleichgewichtskurven. Pflugers Arch. 1954 Oct 4;259(6):481–498. doi: 10.1007/BF00412913. [DOI] [PubMed] [Google Scholar]
- Versprille A., Harinck E., van Nie C. J., Jansen J. R., de Neef K. J. Cross talk between right and left ventricle during the neonatal period. Arch Int Physiol Biochim. 1974;82(2):329–331. [PubMed] [Google Scholar]